Entity Details

Primary name CREM_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ03060
EntryNameCREM_HUMAN
FullNamecAMP-responsive element modulator
TaxID9606
Evidenceevidence at protein level
Length345
SequenceStatuscomplete
DateCreated1994-06-01
DateModified2021-06-02

Ontological Relatives

GenesCREM

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0003677 DNA binding
GO:0005634 nucleus
GO:0005667 transcription regulator complex
GO:0005737 cytoplasm
GO:0006006 glucose metabolic process
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006631 fatty acid metabolic process
GO:0007165 signal transduction
GO:0007275 multicellular organism development
GO:0007283 spermatogenesis
GO:0008140 cAMP response element binding protein binding
GO:0030154 cell differentiation
GO:0042752 regulation of circadian rhythm
GO:0048384 retinoic acid receptor signaling pathway
GO:0048511 rhythmic process
GO:1990589 ATF4-CREB1 transcription factor complex
GO:1990837 sequence-specific double-stranded DNA binding

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR001630 cAMP response element binding (CREB) proteinFamilyFamily
IPR003102 Coactivator CBP, pKIDDomainDomain
IPR004827 Basic-leucine zipper domainDomainDomain

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
CREM_HUMANHDAC1_MOUSEIntAct17056544 details