Entity Details

Primary name CALR_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP14211
EntryNameCALR_MOUSE
FullNameCalreticulin
TaxID10090
Evidenceevidence at protein level
Length416
SequenceStatuscomplete
DateCreated1990-01-01
DateModified2021-06-02

Ontological Relatives

GenesCalr

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0001669 acrosomal vesicle
GO:0002502 peptide antigen assembly with MHC class I protein complex
GO:0003729 mRNA binding
GO:0005178 integrin binding
GO:0005506 iron ion binding
GO:0005509 calcium ion binding
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005635 nuclear envelope
GO:0005737 cytoplasm
GO:0005783 endoplasmic reticulum
GO:0005788 endoplasmic reticulum lumen
GO:0005789 endoplasmic reticulum membrane
GO:0005790 smooth endoplasmic reticulum
GO:0005794 Golgi apparatus
GO:0005829 cytosol
GO:0005844 polysome
GO:0006457 protein folding
GO:0006611 protein export from nucleus
GO:0007283 spermatogenesis
GO:0008284 positive regulation of cell population proliferation
GO:0009897 external side of plasma membrane
GO:0009986 cell surface
GO:0010595 positive regulation of endothelial cell migration
GO:0010628 positive regulation of gene expression
GO:0016020 membrane
GO:0016529 sarcoplasmic reticulum
GO:0017148 negative regulation of translation
GO:0030133 transport vesicle
GO:0030246 carbohydrate binding
GO:0030866 cortical actin cytoskeleton organization
GO:0030968 endoplasmic reticulum unfolded protein response
GO:0031625 ubiquitin protein ligase binding
GO:0032355 response to estradiol
GO:0032991 protein-containing complex
GO:0033018 sarcoplasmic reticulum lumen
GO:0033144 negative regulation of intracellular steroid hormone receptor signaling pathway
GO:0033574 response to testosterone
GO:0034504 protein localization to nucleus
GO:0040020 regulation of meiotic nuclear division
GO:0042277 peptide binding
GO:0042493 response to drug
GO:0042562 hormone binding
GO:0042824 MHC class I peptide loading complex
GO:0043231 intracellular membrane-bounded organelle
GO:0044322 endoplasmic reticulum quality control compartment
GO:0045335 phagocytic vesicle
GO:0045665 negative regulation of neuron differentiation
GO:0045787 positive regulation of cell cycle
GO:0045892 negative regulation of transcription, DNA-templated
GO:0048387 negative regulation of retinoic acid receptor signaling pathway
GO:0048471 perinuclear region of cytoplasm
GO:0050681 androgen receptor binding
GO:0050766 positive regulation of phagocytosis
GO:0050821 protein stabilization
GO:0051082 unfolded protein binding
GO:0055007 cardiac muscle cell differentiation
GO:0060473 cortical granule
GO:0062023 collagen-containing extracellular matrix
GO:0071285 cellular response to lithium ion
GO:0090398 cellular senescence
GO:1900026 positive regulation of substrate adhesion-dependent cell spreading
GO:1901164 negative regulation of trophoblast cell migration
GO:1901224 positive regulation of NIK/NF-kappaB signaling
GO:2000510 positive regulation of dendritic cell chemotaxis

Subcellular Location

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Subcellular Location
Cell surface
Cytolytic granule
Cytoplasm
Cytoplasmic vesicle
Endoplasmic reticulum lumen
Sarcoplasmic reticulum lumen
Secreted

Domains

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DomainNameCategoryType
IPR001580 Calreticulin/calnexinFamilyFamily
IPR009033 Calreticulin/calnexin, P domain superfamilyFamilyHomologous superfamily
IPR009169 CalreticulinFamilyFamily
IPR013320 Concanavalin A-like lectin/glucanase domain superfamilyFamilyHomologous superfamily
IPR018124 Calreticulin/calnexin, conserved siteSiteConserved site

Diseases

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