Entity Details

Primary name SRY_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ05066
EntryNameSRY_HUMAN
FullNameSex-determining region Y protein
TaxID9606
Evidenceevidence at protein level
Length204
SequenceStatuscomplete
DateCreated1994-06-01
DateModified2021-06-02

Ontological Relatives

GenesSRY

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003677 DNA binding
GO:0005516 calmodulin binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0006355 regulation of transcription, DNA-templated
GO:0007548 sex differentiation
GO:0008134 transcription factor binding
GO:0009653 anatomical structure morphogenesis
GO:0010628 positive regulation of gene expression
GO:0016607 nuclear speck
GO:0030154 cell differentiation
GO:0030238 male sex determination
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:2000020 positive regulation of male gonad development

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus
Nucleus speckle

Domains

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DomainNameCategoryType
IPR009071 High mobility group box domainDomainDomain
IPR017253 Transcription factor SRYFamilyFamily
IPR036910 High mobility group box domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
SRY_HUMANXPO4_MOUSEBioGRID19349578 details