Entity Details

Primary name MECOM_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP14404
EntryNameMECOM_MOUSE
FullNameHistone-lysine N-methyltransferase MECOM
TaxID10090
Evidenceevidence at protein level
Length1232
SequenceStatuscomplete
DateCreated1990-01-01
DateModified2021-06-02

Ontological Relatives

GenesMecom

GO terms

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GOName
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001701 in utero embryonic development
GO:0001780 neutrophil homeostasis
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006915 apoptotic process
GO:0006954 inflammatory response
GO:0009617 response to bacterium
GO:0009791 post-embryonic development
GO:0016607 nuclear speck
GO:0030154 cell differentiation
GO:0030900 forebrain development
GO:0035115 embryonic forelimb morphogenesis
GO:0035116 embryonic hindlimb morphogenesis
GO:0042127 regulation of cell population proliferation
GO:0042803 protein homodimerization activity
GO:0043069 negative regulation of programmed cell death
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046329 negative regulation of JNK cascade
GO:0046872 metal ion binding
GO:0046974 histone methyltransferase activity (H3-K9 specific)
GO:0051726 regulation of cell cycle
GO:0060039 pericardium development
GO:0070828 heterochromatin organization
GO:0071425 hematopoietic stem cell proliferation
GO:0072197 ureter morphogenesis
GO:0090336 positive regulation of brown fat cell differentiation
GO:0098727 maintenance of cell number

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus
Nucleus speckle

Domains

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DomainNameCategoryType
IPR001214 SET domainDomainDomain
IPR013087 Zinc finger C2H2-typeDomainDomain
IPR036236 Zinc finger C2H2 superfamilyFamilyHomologous superfamily

Diseases

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