Entity Details

Primary name RING1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ06587
EntryNameRING1_HUMAN
FullNameE3 ubiquitin-protein ligase RING1
TaxID9606
Evidenceevidence at protein level
Length406
SequenceStatuscomplete
DateCreated1994-06-01
DateModified2021-06-02

Ontological Relatives

GenesRING1

GO terms

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GOName
GO:0000151 ubiquitin ligase complex
GO:0001739 sex chromatin
GO:0003682 chromatin binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005829 cytosol
GO:0009952 anterior/posterior pattern specification
GO:0016607 nuclear speck
GO:0031519 PcG protein complex
GO:0035102 PRC1 complex
GO:0035518 histone H2A monoubiquitination
GO:0045892 negative regulation of transcription, DNA-templated
GO:0046872 metal ion binding
GO:0048593 camera-type eye morphogenesis
GO:0061630 ubiquitin protein ligase activity
GO:0070317 negative regulation of G0 to G1 transition
GO:0097027 ubiquitin-protein transferase activator activity

Subcellular Location

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Subcellular Location
Nucleus
Nucleus speckle

Domains

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DomainNameCategoryType
IPR001841 Zinc finger, RING-typeDomainDomain
IPR013083 Zinc finger, RING/FYVE/PHD-typeFamilyHomologous superfamily
IPR017907 Zinc finger, RING-type, conserved siteSiteConserved site
IPR032443 RAWUL domainDomainDomain
IPR042741 RING1 , RING finger, HC subclassDomainDomain
IPR043540 E3 ubiquitin-protein ligase RING1/RING2FamilyFamily

Diseases

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Interactions

3 interactions

InteractorPartnerSourcesPublicationsLink
RING1_HUMANBMI1_MOUSEBioGRID, UniProt12167701 12589020 details
RING1_HUMANFHL1_MOUSEBioGRID, MINT15710417 details
RING1_HUMANTRPM7_MOUSEIntAct24855944 details