Entity Details

Primary name PRDX1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ06830
EntryNamePRDX1_HUMAN
FullNamePeroxiredoxin-1
TaxID9606
Evidenceevidence at protein level
Length199
SequenceStatuscomplete
DateCreated1994-06-01
DateModified2021-06-02

Ontological Relatives

GenesPRDX1

GO terms

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GOName
GO:0001501 skeletal system development
GO:0001895 retina homeostasis
GO:0003723 RNA binding
GO:0004601 peroxidase activity
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0008283 cell population proliferation
GO:0008379 thioredoxin peroxidase activity
GO:0019430 removal of superoxide radicals
GO:0030101 natural killer cell activation
GO:0034599 cellular response to oxidative stress
GO:0042470 melanosome
GO:0042744 hydrogen peroxide catabolic process
GO:0045296 cadherin binding
GO:0045321 leukocyte activation
GO:0045454 cell redox homeostasis
GO:0070062 extracellular exosome

Subcellular Location

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Subcellular Location
Cytoplasm
Melanosome

Domains

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DomainNameCategoryType
IPR000866 Alkyl hydroperoxide reductase subunit C/ Thiol specific antioxidantDomainDomain
IPR013766 Thioredoxin domainDomainDomain
IPR019479 Peroxiredoxin, C-terminalDomainDomain
IPR024706 Peroxiredoxin, AhpC-typeFamilyFamily
IPR036249 Thioredoxin-like superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB01593 ZincDrugbanksmall molecule
DB09130 CopperDrugbanksmall molecule
DB09221 PolaprezincDrugbanksmall molecule
DB11638 ArtenimolDrugbanksmall molecule
DB14487 Zinc acetateDrugbanksmall molecule
DB14533 Zinc chlorideDrugbanksmall molecule
DB14548 Zinc sulfate, unspecified formDrugbanksmall molecule

Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
PRDX1_HUMANMYC_MOUSEBioGRID12196529 details