Entity Details

Primary name RBL2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ08999
EntryNameRBL2_HUMAN
FullNameRetinoblastoma-like protein 2
TaxID9606
Evidenceevidence at protein level
Length1139
SequenceStatuscomplete
DateCreated1995-11-01
DateModified2021-06-02

Ontological Relatives

GenesRBL2

GO terms

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GOName
GO:0000785 chromatin
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0005654 nucleoplasm
GO:0005667 transcription regulator complex
GO:0005694 chromosome
GO:0005730 nucleolus
GO:0005829 cytosol
GO:0006325 chromatin organization
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0010629 negative regulation of gene expression
GO:0030154 cell differentiation
GO:0043550 regulation of lipid kinase activity
GO:0051302 regulation of cell division
GO:0070062 extracellular exosome
GO:1990841 promoter-specific chromatin binding
GO:2000134 negative regulation of G1/S transition of mitotic cell cycle

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR002719 Retinoblastoma-associated protein, B-boxDomainDomain
IPR002720 Retinoblastoma-associated protein, A-boxDomainDomain
IPR013763 Cyclin-likeDomainDomain
IPR015030 Retinoblastoma-associated protein, C-terminalDomainDomain
IPR024599 Retinoblastoma-associated protein, N-terminalDomainDomain
IPR028308 Retinoblastoma-like protein 2FamilyFamily
IPR028309 Retinoblastoma protein familyFamilyFamily
IPR036915 Cyclin-like superfamilyFamilyHomologous superfamily

Diseases

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