Entity Details

Primary name AKP13_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ12802
EntryNameAKP13_HUMAN
FullNameA-kinase anchor protein 13
TaxID9606
Evidenceevidence at protein level
Length2813
SequenceStatuscomplete
DateCreated1999-07-15
DateModified2021-06-02

Ontological Relatives

GenesAKAP13

GO terms

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GOName
GO:0004691 cAMP-dependent protein kinase activity
GO:0005078 MAP-kinase scaffold activity
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005634 nucleus
GO:0005829 cytosol
GO:0005938 cell cortex
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007507 heart development
GO:0016020 membrane
GO:0031267 small GTPase binding
GO:0035023 regulation of Rho protein signal transduction
GO:0035025 positive regulation of Rho protein signal transduction
GO:0035556 intracellular signal transduction
GO:0043065 positive regulation of apoptotic process
GO:0043123 positive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0043406 positive regulation of MAP kinase activity
GO:0046872 metal ion binding
GO:0048471 perinuclear region of cytoplasm
GO:0051018 protein kinase A binding
GO:0051056 regulation of small GTPase mediated signal transduction
GO:0051168 nuclear export
GO:0055007 cardiac muscle cell differentiation
GO:0060090 molecular adaptor activity
GO:0060297 regulation of sarcomere organization
GO:0060348 bone development
GO:0061049 cell growth involved in cardiac muscle cell development
GO:0071875 adrenergic receptor signaling pathway
GO:0086023 adenylate cyclase-activating adrenergic receptor signaling pathway involved in heart process

Subcellular Location

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Subcellular Location
Cytoplasm
Membrane
Nucleus

Domains

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DomainNameCategoryType
IPR000219 Dbl homology (DH) domainDomainDomain
IPR001849 Pleckstrin homology domainDomainDomain
IPR002219 Protein kinase C-like, phorbol ester/diacylglycerol-binding domainDomainDomain
IPR011993 PH-like domain superfamilyFamilyHomologous superfamily
IPR018459 RII binding domainDomainDomain
IPR028852 A-kinase anchor protein 13FamilyFamily
IPR035899 Dbl homology (DH) domain superfamilyFamilyHomologous superfamily
IPR041020 ARHGEF1-like, PH domainDomainDomain

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
AKP13_HUMANPPARA_MOUSEUniProt9627117 details