Entity Details

Primary name CHD3_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ12873
EntryNameCHD3_HUMAN
FullNameChromodomain-helicase-DNA-binding protein 3
TaxID9606
Evidenceevidence at protein level
Length2000
SequenceStatuscomplete
DateCreated1999-07-15
DateModified2021-06-02

Ontological Relatives

GenesCHD3

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000976 transcription cis-regulatory region binding
GO:0003677 DNA binding
GO:0003678 DNA helicase activity
GO:0003723 RNA binding
GO:0004386 helicase activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005730 nucleolus
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0006333 chromatin assembly or disassembly
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007051 spindle organization
GO:0007098 centrosome cycle
GO:0008270 zinc ion binding
GO:0016581 NuRD complex
GO:0016605 PML body
GO:0016887 ATP hydrolysis activity
GO:0034451 centriolar satellite
GO:0036121 double-stranded DNA helicase activity
GO:0043044 ATP-dependent chromatin remodeling
GO:0070615 nucleosome-dependent ATPase activity
GO:1901796 regulation of signal transduction by p53 class mediator

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR000330 SNF2, N-terminalDomainDomain
IPR000953 Chromo/chromo shadow domainDomainDomain
IPR001650 Helicase, C-terminalDomainDomain
IPR001965 Zinc finger, PHD-typeDomainDomain
IPR002464 DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved siteSiteConserved site
IPR009462 Domain of unknown function DUF1086DomainDomain
IPR009463 Domain of unknown function DUF1087DomainDomain
IPR011011 Zinc finger, FYVE/PHD-typeFamilyHomologous superfamily
IPR012957 CHD, C-terminal 2DomainDomain
IPR012958 CHD, N-terminalDomainDomain
IPR013083 Zinc finger, RING/FYVE/PHD-typeFamilyHomologous superfamily
IPR014001 Helicase superfamily 1/2, ATP-binding domainDomainDomain
IPR016197 Chromo-like domain superfamilyFamilyHomologous superfamily
IPR019786 Zinc finger, PHD-type, conserved siteSiteConserved site
IPR019787 Zinc finger, PHD-fingerDomainDomain
IPR023779 Chromo domain, conserved siteSiteConserved site
IPR023780 Chromo domainDomainDomain
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR036910 High mobility group box domain superfamilyFamilyHomologous superfamily
IPR038718 SNF2-like, N-terminal domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
CHD3_HUMANP53_MOUSEIntAct15383276 details