Entity Details

Primary name HMOX1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP14901
EntryNameHMOX1_MOUSE
FullNameHeme oxygenase 1
TaxID10090
Evidenceevidence at protein level
Length289
SequenceStatuscomplete
DateCreated1990-04-01
DateModified2021-06-02

Ontological Relatives

GenesHmox1

GO terms

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GOName
GO:0001525 angiogenesis
GO:0001666 response to hypoxia
GO:0002246 wound healing involved in inflammatory response
GO:0004392 heme oxygenase (decyclizing) activity
GO:0004630 phospholipase D activity
GO:0005198 structural molecule activity
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0005829 cytosol
GO:0005901 caveola
GO:0006788 heme oxidation
GO:0006879 cellular iron ion homeostasis
GO:0006979 response to oxidative stress
GO:0007264 small GTPase mediated signal transduction
GO:0008217 regulation of blood pressure
GO:0008219 cell death
GO:0008285 negative regulation of cell population proliferation
GO:0008630 intrinsic apoptotic signaling pathway in response to DNA damage
GO:0010656 negative regulation of muscle cell apoptotic process
GO:0016239 positive regulation of macroautophagy
GO:0016242 negative regulation of macroautophagy
GO:0019899 enzyme binding
GO:0020037 heme binding
GO:0031670 cellular response to nutrient
GO:0032764 negative regulation of mast cell cytokine production
GO:0034101 erythrocyte homeostasis
GO:0034395 regulation of transcription from RNA polymerase II promoter in response to iron
GO:0034605 cellular response to heat
GO:0035094 response to nicotine
GO:0035556 intracellular signal transduction
GO:0042167 heme catabolic process
GO:0042168 heme metabolic process
GO:0042493 response to drug
GO:0042542 response to hydrogen peroxide
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0043065 positive regulation of apoptotic process
GO:0043305 negative regulation of mast cell degranulation
GO:0043392 negative regulation of DNA binding
GO:0043433 negative regulation of DNA-binding transcription factor activity
GO:0043524 negative regulation of neuron apoptotic process
GO:0043619 regulation of transcription from RNA polymerase II promoter in response to oxidative stress
GO:0043627 response to estrogen
GO:0045766 positive regulation of angiogenesis
GO:0046872 metal ion binding
GO:0048471 perinuclear region of cytoplasm
GO:0048661 positive regulation of smooth muscle cell proliferation
GO:0048662 negative regulation of smooth muscle cell proliferation
GO:0051090 regulation of DNA-binding transcription factor activity
GO:0055072 iron ion homeostasis
GO:0071243 cellular response to arsenic-containing substance
GO:0071276 cellular response to cadmium ion
GO:0071456 cellular response to hypoxia
GO:0072719 cellular response to cisplatin
GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis
GO:0097421 liver regeneration
GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
GO:1903589 positive regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis
GO:1904036 negative regulation of epithelial cell apoptotic process
GO:1904706 negative regulation of vascular associated smooth muscle cell proliferation

Subcellular Location

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Subcellular Location
Endoplasmic reticulum membrane
Microsome

Domains

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DomainNameCategoryType
IPR002051 Haem oxygenaseFamilyFamily
IPR016053 Haem oxygenase-likeFamilyFamily
IPR016084 Haem oxygenase-like, multi-helicalFamilyHomologous superfamily
IPR018207 Haem oxygenase conserved siteSiteConserved site

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
HMOX1_MOUSECALX_MOUSEMINT22045338 details