Entity Details

Primary name PTPRJ_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ12913
EntryNamePTPRJ_HUMAN
FullNameReceptor-type tyrosine-protein phosphatase eta
TaxID9606
Evidenceevidence at protein level
Length1337
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesPTPRJ

GO terms

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GOName
GO:0001772 immunological synapse
GO:0004725 protein tyrosine phosphatase activity
GO:0005161 platelet-derived growth factor receptor binding
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0005911 cell-cell junction
GO:0006470 protein dephosphorylation
GO:0008013 beta-catenin binding
GO:0008285 negative regulation of cell population proliferation
GO:0009986 cell surface
GO:0010642 negative regulation of platelet-derived growth factor receptor signaling pathway
GO:0016791 phosphatase activity
GO:0019221 cytokine-mediated signaling pathway
GO:0019901 protein kinase binding
GO:0030155 regulation of cell adhesion
GO:0030183 B cell differentiation
GO:0030308 negative regulation of cell growth
GO:0030336 negative regulation of cell migration
GO:0032587 ruffle membrane
GO:0032760 positive regulation of tumor necrosis factor production
GO:0035335 peptidyl-tyrosine dephosphorylation
GO:0035579 specific granule membrane
GO:0035584 calcium-mediated signaling using intracellular calcium source
GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway
GO:0043116 negative regulation of vascular permeability
GO:0043312 neutrophil degranulation
GO:0043407 negative regulation of MAP kinase activity
GO:0043410 positive regulation of MAPK cascade
GO:0045295 gamma-catenin binding
GO:0045296 cadherin binding
GO:0045785 positive regulation of cell adhesion
GO:0048008 platelet-derived growth factor receptor signaling pathway
GO:0050731 positive regulation of peptidyl-tyrosine phosphorylation
GO:0050852 T cell receptor signaling pathway
GO:0050860 negative regulation of T cell receptor signaling pathway
GO:0050918 positive chemotaxis
GO:0051019 mitogen-activated protein kinase binding
GO:0051894 positive regulation of focal adhesion assembly
GO:0051897 positive regulation of protein kinase B signaling
GO:0051898 negative regulation of protein kinase B signaling
GO:0060242 contact inhibition
GO:0070062 extracellular exosome
GO:0070097 delta-catenin binding
GO:1905451 positive regulation of Fc-gamma receptor signaling pathway involved in phagocytosis

Subcellular Location

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Subcellular Location
Cell junction
Cell membrane
Cell projection

Domains

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DomainNameCategoryType
IPR000242 PTP type protein phosphataseDomainDomain
IPR000387 Tyrosine specific protein phosphatases domainDomainDomain
IPR003595 Protein-tyrosine phosphatase, catalyticDomainDomain
IPR003961 Fibronectin type IIIDomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR016130 Protein-tyrosine phosphatase, active siteSiteActive site
IPR029021 Protein-tyrosine phosphatase-likeFamilyHomologous superfamily
IPR036116 Fibronectin type III superfamilyFamilyHomologous superfamily
IPR041201 PTPRJ, transmembrane domainDomainDomain

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
PTPRJ_HUMANLEPR_MOUSEIntAct19167335 details