Entity Details

Primary name CADH2_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP15116
EntryNameCADH2_MOUSE
FullNameCadherin-2
TaxID10090
Evidenceevidence at protein level
Length906
SequenceStatuscomplete
DateCreated1990-04-01
DateModified2021-06-02

Ontological Relatives

GenesCdh2

GO terms

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GOName
GO:0003323 type B pancreatic cell development
GO:0005509 calcium ion binding
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0005911 cell-cell junction
GO:0005912 adherens junction
GO:0005916 fascia adherens
GO:0007043 cell-cell junction assembly
GO:0007155 cell adhesion
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules
GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
GO:0007416 synapse assembly
GO:0007420 brain development
GO:0008013 beta-catenin binding
GO:0009986 cell surface
GO:0010001 glial cell differentiation
GO:0014032 neural crest cell development
GO:0014069 postsynaptic density
GO:0014704 intercalated disc
GO:0016020 membrane
GO:0016323 basolateral plasma membrane
GO:0016324 apical plasma membrane
GO:0016327 apicolateral plasma membrane
GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules
GO:0016342 catenin complex
GO:0016477 cell migration
GO:0019899 enzyme binding
GO:0019901 protein kinase binding
GO:0019903 protein phosphatase binding
GO:0021537 telencephalon development
GO:0021987 cerebral cortex development
GO:0030027 lamellipodium
GO:0030054 cell junction
GO:0030315 T-tubule
GO:0030864 cortical actin cytoskeleton
GO:0031641 regulation of myelination
GO:0032880 regulation of protein localization
GO:0032991 protein-containing complex
GO:0035023 regulation of Rho protein signal transduction
GO:0042383 sarcolemma
GO:0042802 identical protein binding
GO:0043005 neuron projection
GO:0043410 positive regulation of MAPK cascade
GO:0044331 cell-cell adhesion mediated by cadherin
GO:0044853 plasma membrane raft
GO:0044877 protein-containing complex binding
GO:0045177 apical part of cell
GO:0045202 synapse
GO:0045294 alpha-catenin binding
GO:0045295 gamma-catenin binding
GO:0045296 cadherin binding
GO:0048514 blood vessel morphogenesis
GO:0048854 brain morphogenesis
GO:0048872 homeostasis of number of cells
GO:0050770 regulation of axonogenesis
GO:0050804 modulation of chemical synaptic transmission
GO:0050998 nitric-oxide synthase binding
GO:0051146 striated muscle cell differentiation
GO:0051966 regulation of synaptic transmission, glutamatergic
GO:0060019 radial glial cell differentiation
GO:0060563 neuroepithelial cell differentiation
GO:0070445 regulation of oligodendrocyte progenitor proliferation
GO:0072659 protein localization to plasma membrane
GO:0090090 negative regulation of canonical Wnt signaling pathway
GO:0090497 mesenchymal cell migration
GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly
GO:0097150 neuronal stem cell population maintenance
GO:0098609 cell-cell adhesion
GO:0098742 cell-cell adhesion via plasma-membrane adhesion molecules
GO:0098978 glutamatergic synapse
GO:0099059 integral component of presynaptic active zone membrane
GO:0099060 integral component of postsynaptic specialization membrane
GO:1902897 regulation of postsynaptic density protein 95 clustering
GO:2000809 positive regulation of synaptic vesicle clustering

Subcellular Location

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Subcellular Location
Cell junction
Cell membrane
Cell surface

Domains

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DomainNameCategoryType
IPR000233 Cadherin, cytoplasmic domainDomainDomain
IPR002126 Cadherin-likeDomainDomain
IPR014868 Cadherin prodomainDomainDomain
IPR015919 Cadherin-like superfamilyFamilyHomologous superfamily
IPR020894 Cadherin conserved siteSiteConserved site
IPR027397 Catenin binding domain superfamilyFamilyHomologous superfamily
IPR030051 N-cadherinFamilyFamily
IPR039808 CadherinFamilyFamily

Diseases

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