Entity Details

Primary name TADBP_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ13148
EntryNameTADBP_HUMAN
FullNameTAR DNA-binding protein 43
TaxID9606
Evidenceevidence at protein level
Length414
SequenceStatuscomplete
DateCreated2002-03-27
DateModified2021-06-02

Ontological Relatives

GenesTARDBP

GO terms

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GOName
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0001933 negative regulation of protein phosphorylation
GO:0003690 double-stranded DNA binding
GO:0003723 RNA binding
GO:0003730 mRNA 3'-UTR binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005726 perichromatin fibrils
GO:0006397 mRNA processing
GO:0008380 RNA splicing
GO:0010468 regulation of gene expression
GO:0010494 cytoplasmic stress granule
GO:0010629 negative regulation of gene expression
GO:0016607 nuclear speck
GO:0031647 regulation of protein stability
GO:0032024 positive regulation of insulin secretion
GO:0034976 response to endoplasmic reticulum stress
GO:0035061 interchromatin granule
GO:0042307 positive regulation of protein import into nucleus
GO:0042752 regulation of circadian rhythm
GO:0042802 identical protein binding
GO:0042981 regulation of apoptotic process
GO:0043922 negative regulation by host of viral transcription
GO:0048511 rhythmic process
GO:0051726 regulation of cell cycle
GO:0061158 3'-UTR-mediated mRNA destabilization
GO:0070935 3'-UTR-mediated mRNA stabilization
GO:0071765 nuclear inner membrane organization
GO:0097157 pre-mRNA intronic binding

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR000504 RNA recognition motif domainDomainDomain
IPR012677 Nucleotide-binding alpha-beta plait domain superfamilyFamilyHomologous superfamily
IPR035979 RNA-binding domain superfamilyFamilyHomologous superfamily
IPR041105 TAR DNA-binding protein 43, N-terminalDomainDomain

Diseases

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Interactions

3 interactions