Entity Details

Primary name REL_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP15307
EntryNameREL_MOUSE
FullNameProto-oncogene c-Rel
TaxID10090
Evidenceevidence at protein level
Length587
SequenceStatuscomplete
DateCreated1990-04-01
DateModified2021-04-07

Ontological Relatives

GO terms

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GOName
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0005667 transcription regulator complex
GO:0005737 cytoplasm
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006954 inflammatory response
GO:0007249 I-kappaB kinase/NF-kappaB signaling
GO:0010629 negative regulation of gene expression
GO:0032688 negative regulation of interferon-beta production
GO:0032735 positive regulation of interleukin-12 production
GO:0034097 response to cytokine
GO:0038061 NIK/NF-kappaB signaling
GO:0043565 sequence-specific DNA binding
GO:0045087 innate immune response
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:1901215 negative regulation of neuron death

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR000451 NF-kappa-B/DorsalFamilyFamily
IPR002909 IPT domainDomainDomain
IPR008967 p53-like transcription factor, DNA-bindingFamilyHomologous superfamily
IPR011539 Rel homology domain (RHD), DNA-binding domainDomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR014756 Immunoglobulin E-setFamilyHomologous superfamily
IPR030492 Rel homology domain, conserved siteSiteConserved site
IPR030505 Proto-oncogene c-RelFamilyFamily
IPR032397 Rel homology dimerisation domainDomainDomain
IPR033926 NFkappaB IPT domainDomainDomain
IPR037059 Rel homology domain (RHD), DNA-binding domain superfamilyFamilyHomologous superfamily
IPR042845 Proto-oncogene c-Rel, RHD, N-terminal subdomainDomainDomain

Diseases

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Interactions

3 interactions