Entity Details

Primary name SRSF6_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ13247
EntryNameSRSF6_HUMAN
FullNameSerine/arginine-rich splicing factor 6
TaxID9606
Evidenceevidence at protein level
Length344
SequenceStatuscomplete
DateCreated1998-12-15
DateModified2021-06-02

Ontological Relatives

GenesSRSF6

GO terms

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GOName
GO:0000380 alternative mRNA splicing, via spliceosome
GO:0000381 regulation of alternative mRNA splicing, via spliceosome
GO:0000398 mRNA splicing, via spliceosome
GO:0003723 RNA binding
GO:0003729 mRNA binding
GO:0005654 nucleoplasm
GO:0006376 mRNA splice site selection
GO:0006405 RNA export from nucleus
GO:0006406 mRNA export from nucleus
GO:0010837 regulation of keratinocyte proliferation
GO:0016607 nuclear speck
GO:0031124 mRNA 3'-end processing
GO:0032868 response to insulin
GO:0036002 pre-mRNA binding
GO:0045617 negative regulation of keratinocyte differentiation
GO:0048025 negative regulation of mRNA splicing, via spliceosome
GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis
GO:0060548 negative regulation of cell death
GO:0061041 regulation of wound healing
GO:2000675 negative regulation of type B pancreatic cell apoptotic process

Subcellular Location

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Subcellular Location
Nucleus
Nucleus speckle

Domains

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DomainNameCategoryType
IPR000504 RNA recognition motif domainDomainDomain
IPR012677 Nucleotide-binding alpha-beta plait domain superfamilyFamilyHomologous superfamily
IPR029541 Serine/arginine-rich splicing factor 6FamilyFamily
IPR034511 SRSF6, RNA recognition motif 1DomainDomain
IPR035979 RNA-binding domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
SRSF6_HUMANRRP1B_MOUSEBioGRID19710015 details