Entity Details

Primary name TIF1B_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ13263
EntryNameTIF1B_HUMAN
FullNameTranscription intermediary factor 1-beta
TaxID9606
Evidenceevidence at protein level
Length835
SequenceStatuscomplete
DateCreated1998-07-15
DateModified2021-06-02

Ontological Relatives

GenesTRIM28

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0000791 euchromatin
GO:0000792 heterochromatin
GO:0001837 epithelial to mesenchymal transition
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0003713 transcription coactivator activity
GO:0003714 transcription corepressor activity
GO:0003723 RNA binding
GO:0004672 protein kinase activity
GO:0004842 ubiquitin-protein transferase activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0006281 DNA repair
GO:0006325 chromatin organization
GO:0007265 Ras protein signal transduction
GO:0007566 embryo implantation
GO:0008270 zinc ion binding
GO:0016032 viral process
GO:0016925 protein sumoylation
GO:0019789 SUMO transferase activity
GO:0031625 ubiquitin protein ligase binding
GO:0032991 protein-containing complex
GO:0035851 Krueppel-associated box domain binding
GO:0042307 positive regulation of protein import into nucleus
GO:0043045 DNA methylation involved in embryo development
GO:0043388 positive regulation of DNA binding
GO:0045087 innate immune response
GO:0045739 positive regulation of DNA repair
GO:0045869 negative regulation of single stranded viral RNA replication via double stranded DNA intermediate
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:0046777 protein autophosphorylation
GO:0060028 convergent extension involved in axis elongation
GO:0060260 regulation of transcription initiation from RNA polymerase II promoter
GO:0060669 embryonic placenta morphogenesis
GO:0070087 chromo shadow domain binding
GO:0090309 positive regulation of DNA methylation-dependent heterochromatin assembly
GO:0090575 RNA polymerase II transcription regulator complex
GO:1901536 negative regulation of DNA demethylation
GO:1902187 negative regulation of viral release from host cell
GO:1990841 promoter-specific chromatin binding
GO:2000653 regulation of genetic imprinting

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR000315 B-box-type zinc fingerDomainDomain
IPR001487 BromodomainDomainDomain
IPR001841 Zinc finger, RING-typeDomainDomain
IPR001965 Zinc finger, PHD-typeDomainDomain
IPR003649 B-box, C-terminalDomainDomain
IPR011011 Zinc finger, FYVE/PHD-typeFamilyHomologous superfamily
IPR013083 Zinc finger, RING/FYVE/PHD-typeFamilyHomologous superfamily
IPR019786 Zinc finger, PHD-type, conserved siteSiteConserved site
IPR019787 Zinc finger, PHD-fingerDomainDomain
IPR036427 Bromodomain-like superfamilyFamilyHomologous superfamily
IPR037373 Transcription intermediary factor 1-betaFamilyFamily
IPR042713 TIF1-beta, RING finger, HC subclassDomainDomain

Diseases

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