Entity Details

Primary name G3BP1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ13283
EntryNameG3BP1_HUMAN
FullNameRas GTPase-activating protein-binding protein 1
TaxID9606
Evidenceevidence at protein level
Length466
SequenceStatuscomplete
DateCreated2001-07-11
DateModified2021-06-02

Ontological Relatives

GenesG3BP1

GO terms

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GOName
GO:0003677 DNA binding
GO:0003678 DNA helicase activity
GO:0003723 RNA binding
GO:0003724 RNA helicase activity
GO:0003729 mRNA binding
GO:0004519 endonuclease activity
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005925 focal adhesion
GO:0007265 Ras protein signal transduction
GO:0010494 cytoplasmic stress granule
GO:0016032 viral process
GO:0032481 positive regulation of type I interferon production
GO:0033677 DNA/RNA helicase activity
GO:0034063 stress granule assembly
GO:0043204 perikaryon
GO:0045087 innate immune response
GO:0051607 defense response to virus
GO:0062029 positive regulation of stress granule assembly
GO:1990904 ribonucleoprotein complex

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus
Perikaryon

Domains

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DomainNameCategoryType
IPR000504 RNA recognition motif domainDomainDomain
IPR002075 Nuclear transport factor 2DomainDomain
IPR018222 Nuclear transport factor 2, eukaryoteDomainDomain
IPR032710 NTF2-like domain superfamilyFamilyHomologous superfamily
IPR034374 G3BP1, RNA recognition motifDomainDomain
IPR034375 Ras GTPase-activating protein-binding protein 1FamilyFamily
IPR035979 RNA-binding domain superfamilyFamilyHomologous superfamily
IPR039539 Ras GTPase-activating protein-binding proteinFamilyFamily

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
G3BP1_HUMANMK13_MOUSEBioGRID19135240 details
G3BP1_HUMANUBP10_MOUSEBioGRID23230274 details