Entity Details

Primary name CTBP1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ13363
EntryNameCTBP1_HUMAN
FullNameC-terminal-binding protein 1
TaxID9606
Evidenceevidence at protein level
Length440
SequenceStatuscomplete
DateCreated1998-07-15
DateModified2021-06-02

Ontological Relatives

GenesCTBP1

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0003714 transcription corepressor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0006342 chromatin silencing
GO:0006468 protein phosphorylation
GO:0008022 protein C-terminus binding
GO:0008134 transcription factor binding
GO:0008285 negative regulation of cell population proliferation
GO:0016616 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0017053 transcription repressor complex
GO:0019079 viral genome replication
GO:0019904 protein domain specific binding
GO:0031065 positive regulation of histone deacetylation
GO:0035067 negative regulation of histone acetylation
GO:0042802 identical protein binding
GO:0045892 negative regulation of transcription, DNA-templated
GO:0050872 white fat cell differentiation
GO:0051287 NAD binding
GO:0051726 regulation of cell cycle
GO:0090241 negative regulation of histone H4 acetylation

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domainDomainDomain
IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domainDomainDomain
IPR029752 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1SiteConserved site
IPR029753 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved siteSiteConserved site
IPR036291 NAD(P)-binding domain superfamilyFamilyHomologous superfamily
IPR043322 C-terminal binding proteinFamilyFamily

Diseases

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Drugs

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DrugNameSourceType
DB01942 Formic acidDrugbanksmall molecule

Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
CTBP1_HUMANNRIP1_MOUSEBioGRID11509661 details