Entity Details

Primary name CUL4A_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ13619
EntryNameCUL4A_HUMAN
FullNameCullin-4A
TaxID9606
Evidenceevidence at protein level
Length759
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesCUL4A

GO terms

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GOName
GO:0000082 G1/S transition of mitotic cell cycle
GO:0000715 nucleotide-excision repair, DNA damage recognition
GO:0000717 nucleotide-excision repair, DNA duplex unwinding
GO:0001701 in utero embryonic development
GO:0004842 ubiquitin-protein transferase activity
GO:0005654 nucleoplasm
GO:0006283 transcription-coupled nucleotide-excision repair
GO:0006293 nucleotide-excision repair, preincision complex stabilization
GO:0006294 nucleotide-excision repair, preincision complex assembly
GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion
GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion
GO:0006974 cellular response to DNA damage stimulus
GO:0008284 positive regulation of cell population proliferation
GO:0016032 viral process
GO:0016567 protein ubiquitination
GO:0019005 SCF ubiquitin ligase complex
GO:0030097 hemopoiesis
GO:0030853 negative regulation of granulocyte differentiation
GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0031461 cullin-RING ubiquitin ligase complex
GO:0031464 Cul4A-RING E3 ubiquitin ligase complex
GO:0031625 ubiquitin protein ligase binding
GO:0033683 nucleotide-excision repair, DNA incision
GO:0035019 somatic stem cell population maintenance
GO:0042254 ribosome biogenesis
GO:0042769 DNA damage response, detection of DNA damage
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0043687 post-translational protein modification
GO:0048511 rhythmic process
GO:0051246 regulation of protein metabolic process
GO:0070911 global genome nucleotide-excision repair
GO:0080008 Cul4-RING E3 ubiquitin ligase complex
GO:0097193 intrinsic apoptotic signaling pathway
GO:1900087 positive regulation of G1/S transition of mitotic cell cycle
GO:2000001 regulation of DNA damage checkpoint
GO:2000819 regulation of nucleotide-excision repair

Subcellular Location

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Domains

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DomainNameCategoryType
IPR001373 Cullin, N-terminalDomainDomain
IPR016157 Cullin, conserved siteSiteConserved site
IPR016158 Cullin homology domainDomainDomain
IPR016159 Cullin repeat-like-containing domain superfamilyFamilyHomologous superfamily
IPR019559 Cullin protein, neddylation domainDomainDomain
IPR036317 Cullin homology domain superfamilyFamilyHomologous superfamily
IPR036388 Winged helix-like DNA-binding domain superfamilyFamilyHomologous superfamily
IPR036390 Winged helix DNA-binding domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

0 interactions

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