Entity Details

Primary name ASPP2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ13625
EntryNameASPP2_HUMAN
FullNameApoptosis-stimulating of p53 protein 2
TaxID9606
Evidenceevidence at protein level
Length1128
SequenceStatuscomplete
DateCreated1998-07-15
DateModified2021-06-02

Ontological Relatives

GenesTP53BP2

GO terms

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GOName
GO:0002039 p53 binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005829 cytosol
GO:0007049 cell cycle
GO:0007165 signal transduction
GO:0017124 SH3 domain binding
GO:0030054 cell junction
GO:0042802 identical protein binding
GO:0042981 regulation of apoptotic process
GO:0045786 negative regulation of cell cycle
GO:0048471 perinuclear region of cytoplasm
GO:0051059 NF-kappaB binding
GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator
GO:1900119 positive regulation of execution phase of apoptosis
GO:1900740 positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
GO:1901216 positive regulation of neuron death
GO:1901796 regulation of signal transduction by p53 class mediator

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR001452 SH3 domainDomainDomain
IPR002110 Ankyrin repeatRepeatRepeat
IPR020683 Ankyrin repeat-containing domainDomainDomain
IPR029071 Ubiquitin-like domain superfamilyFamilyHomologous superfamily
IPR036028 SH3-like domain superfamilyFamilyHomologous superfamily
IPR036770 Ankyrin repeat-containing domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
ASPP2_HUMANIRS2_MOUSEIntAct17965023 details
ASPP2_HUMANIRS1_MOUSEIntAct17965023 details