Entity Details

Primary name SPTN1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ13813
EntryNameSPTN1_HUMAN
FullNameSpectrin alpha chain, non-erythrocytic 1
TaxID9606
Evidenceevidence at protein level
Length2472
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesSPTAN1

GO terms

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GOName
GO:0000165 MAPK cascade
GO:0003779 actin binding
GO:0005200 structural constituent of cytoskeleton
GO:0005509 calcium ion binding
GO:0005516 calmodulin binding
GO:0005576 extracellular region
GO:0005829 cytosol
GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport
GO:0007411 axon guidance
GO:0008091 spectrin
GO:0015630 microtubule cytoskeleton
GO:0016020 membrane
GO:0035580 specific granule lumen
GO:0043231 intracellular membrane-bounded organelle
GO:0043312 neutrophil degranulation
GO:0045296 cadherin binding
GO:0051693 actin filament capping
GO:0070062 extracellular exosome
GO:1903561 extracellular vesicle
GO:1904724 tertiary granule lumen

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR001452 SH3 domainDomainDomain
IPR002017 Spectrin repeatRepeatRepeat
IPR002048 EF-hand domainDomainDomain
IPR011992 EF-hand domain pairFamilyHomologous superfamily
IPR014837 EF-hand, Ca insensitiveDomainDomain
IPR018159 Spectrin/alpha-actininRepeatRepeat
IPR018247 EF-Hand 1, calcium-binding siteSiteBinding site
IPR035825 Alpha Spectrin, SH3 domainDomainDomain
IPR036028 SH3-like domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

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