Entity Details

Primary name TFE2_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP15806
EntryNameTFE2_MOUSE
FullNameTranscription factor E2-alpha
TaxID10090
Evidenceevidence at protein level
Length651
SequenceStatuscomplete
DateCreated1990-04-01
DateModified2021-06-02

Ontological Relatives

GenesTcf3

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0000786 nucleosome
GO:0000791 euchromatin
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0000987 cis-regulatory region sequence-specific DNA binding
GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0001779 natural killer cell differentiation
GO:0002326 B cell lineage commitment
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005667 transcription regulator complex
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006366 transcription by RNA polymerase II
GO:0007369 gastrulation
GO:0007399 nervous system development
GO:0008134 transcription factor binding
GO:0010628 positive regulation of gene expression
GO:0030098 lymphocyte differentiation
GO:0030165 PDZ domain binding
GO:0030218 erythrocyte differentiation
GO:0030890 positive regulation of B cell proliferation
GO:0031435 mitogen-activated protein kinase kinase kinase binding
GO:0032496 response to lipopolysaccharide
GO:0032991 protein-containing complex
GO:0033077 T cell differentiation in thymus
GO:0033152 immunoglobulin V(D)J recombination
GO:0042493 response to drug
GO:0042803 protein homodimerization activity
GO:0043425 bHLH transcription factor binding
GO:0043565 sequence-specific DNA binding
GO:0043966 histone H3 acetylation
GO:0043967 histone H4 acetylation
GO:0045666 positive regulation of neuron differentiation
GO:0045787 positive regulation of cell cycle
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046982 protein heterodimerization activity
GO:0048468 cell development
GO:0048541 Peyer's patch development
GO:0050821 protein stabilization
GO:0051091 positive regulation of DNA-binding transcription factor activity
GO:0070644 vitamin D response element binding
GO:0070888 E-box binding
GO:0090575 RNA polymerase II transcription regulator complex
GO:2000045 regulation of G1/S transition of mitotic cell cycle

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR011598 Myc-type, basic helix-loop-helix (bHLH) domainDomainDomain
IPR036638 Helix-loop-helix DNA-binding domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

61 interactions

InteractorPartnerSourcesPublicationsLink
TFE2_MOUSEHAND1_MOUSEIntAct10924525 details
TFE2_MOUSEHAND2_MOUSEBioGRID, IntAct10924525 15351717 details
TFE2_MOUSEID2_MOUSEbhf-ucl, BioGRID, DIP, MINT11591653 12200424 16311606 19321746 23395635 details
TFE2_MOUSEID1_MOUSEMINT11591653 details
TFE2_MOUSEPHLA1_MOUSEMINT11591653 details
TFE2_MOUSETCF21_MOUSEMINT11591653 details
TFE2_MOUSETAL1_MOUSEMINT16407974 details
TFE2_MOUSEMTG16_MOUSEMINT16407974 details
TFE2_MOUSEUBC9_MOUSEBioGRID, IntAct12200424 22354994 9409784 details
TFE2_MOUSETFE2_HUMANBioGRID, IntAct9050988 9409784 details
TFE2_MOUSEFOXP1_MOUSEBioGRID, IntAct20211142 details
TFE2_MOUSEZDH15_MOUSEBioGRID, IntAct20211142 details
TFE2_MOUSETLE6_MOUSEBioGRID, IntAct20211142 details
TFE2_MOUSENS1BP_MOUSEBioGRID, IntAct20211142 details
TFE2_MOUSEMEIS2_MOUSEBioGRID, IntAct20211142 details
TFE2_MOUSENEMO_MOUSEBioGRID, IntAct20211142 details
TFE2_MOUSEELAV2_MOUSEBioGRID, IntAct20211142 details
TFE2_MOUSET22D3_MOUSEBioGRID, IntAct20211142 details
TFE2_MOUSEGFI1_MOUSEBioGRID, IntAct20211142 details
TFE2_MOUSEC2TA_MOUSEBioGRID, IntAct20211142 details
TFE2_MOUSEBRCA1_MOUSEBioGRID, IntAct20211142 details
TFE2_MOUSETAF1B_MOUSEBioGRID, IntAct20211142 details
TFE2_MOUSERPA1_MOUSEBioGRID, IntAct20211142 details
TFE2_MOUSEPHF2_MOUSEBioGRID, IntAct20211142 details
TFE2_MOUSESWAHC_MOUSEBioGRID, IntAct20211142 details
TFE2_MOUSEJADE1_MOUSEBioGRID, IntAct20211142 details
TFE2_MOUSEPDLI4_MOUSEBioGRID, IntAct20211142 details
TFE2_MOUSEZN292_MOUSEBioGRID, IntAct20211142 details
TFE2_MOUSETRIP4_MOUSEBioGRID, IntAct20211142 details
TFE2_MOUSESMCE1_MOUSEBioGRID, IntAct20211142 details
TFE2_MOUSERNF14_MOUSEBioGRID, IntAct20211142 details
TFE2_MOUSEPAPOB_MOUSEBioGRID, IntAct20211142 details
TFE2_MOUSEZDHC6_MOUSEBioGRID, IntAct20211142 details
TFE2_MOUSERFX4_MOUSEBioGRID, IntAct20211142 details
TFE2_MOUSEERCC8_MOUSEBioGRID, IntAct20211142 details
TFE2_MOUSERAI14_MOUSEBioGRID, IntAct20211142 details
TFE2_MOUSECERS2_MOUSEBioGRID, IntAct20211142 details
TFE2_MOUSEPBX4_MOUSEBioGRID, IntAct20211142 details
TFE2_MOUSETRI27_MOUSEBioGRID16007160 details
TFE2_MOUSEASCL1_MOUSEBioGRID12200424 12217327 20211142 8948587 details
TFE2_MOUSEMYOD1_MOUSEBioGRID11711431 20211142 details
TFE2_MOUSETFE2_MOUSEBioGRID15351717 17339447 20211142 details
TFE2_MOUSEASCL3_MOUSEBioGRID11784080 20211142 details
TFE2_MOUSEBHE41_MOUSEBioGRID12657651 details
TFE2_MOUSEID3_MOUSEBioGRID22354994 8759016 details
TFE2_MOUSEASCL3_HUMANBioGRID11784080 details
TFE2_MOUSEITF2_MOUSEBioGRID15351717 details
TFE2_MOUSEHTF4_MOUSEBioGRID15351717 details
TFE2_MOUSEFER3L_MOUSEBioGRID12217327 details
TFE2_MOUSERGPA1_MOUSEBioGRID12200424 details
TFE2_MOUSENGN2_MOUSEBioGRID8948587 details
TFE2_MOUSETCF15_MOUSEBioGRID23395635 details
TFE2_MOUSETWST1_MOUSEBioGRID23395635 details
TFE2_MOUSENDF1_MOUSEBioGRID23395635 details
TFE2_MOUSERBTN2_MOUSEBioGRID26764384 details
TFE2_MOUSEOLIG1_MOUSEIntAct15280210 details
TFE2_MOUSEOLIG2_MOUSEBioGRID, IntAct15280210 15655114 details
TFE2_MOUSEDACT2_MOUSEUniProt21718540 details
TFE2_MOUSEATOH1_MOUSEDIP17878293 details
TFE2_MOUSECHIP_MOUSEBioGRID15456869 details
TFE2_MOUSEMYSM1_MOUSEBioGRID22169041 details