Entity Details

Primary name ARHG7_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ14155
EntryNameARHG7_HUMAN
FullNameRho guanine nucleotide exchange factor 7
TaxID9606
Evidenceevidence at protein level
Length803
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesARHGEF7

GO terms

Show/Hide Table
GOName
GO:0001726 ruffle
GO:0005085 guanyl-nucleotide exchange factor activity
GO:0005813 centrosome
GO:0005829 cytosol
GO:0005925 focal adhesion
GO:0005938 cell cortex
GO:0007030 Golgi organization
GO:0007165 signal transduction
GO:0007186 G protein-coupled receptor signaling pathway
GO:0007399 nervous system development
GO:0010763 positive regulation of fibroblast migration
GO:0019901 protein kinase binding
GO:0030027 lamellipodium
GO:0030032 lamellipodium assembly
GO:0032991 protein-containing complex
GO:0035556 intracellular signal transduction
GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway
GO:0043005 neuron projection
GO:0043015 gamma-tubulin binding
GO:0043025 neuronal cell body
GO:0043065 positive regulation of apoptotic process
GO:0043547 positive regulation of GTPase activity
GO:0048013 ephrin receptor signaling pathway
GO:0048041 focal adhesion assembly
GO:0051056 regulation of small GTPase mediated signal transduction
GO:0097431 mitotic spindle pole
GO:0098794 postsynapse
GO:1900026 positive regulation of substrate adhesion-dependent cell spreading
GO:1904424 regulation of GTP binding
GO:1905833 negative regulation of microtubule nucleation
GO:2000394 positive regulation of lamellipodium morphogenesis

Subcellular Location

Show/Hide Table
Subcellular Location
Cell junction
Cell projection
Cytoplasm

Domains

Show/Hide Table
DomainNameCategoryType
IPR000219 Dbl homology (DH) domainDomainDomain
IPR001331 Guanine-nucleotide dissociation stimulator, CDC24, conserved siteSiteConserved site
IPR001452 SH3 domainDomainDomain
IPR001715 Calponin homology domainDomainDomain
IPR001849 Pleckstrin homology domainDomainDomain
IPR011993 PH-like domain superfamilyFamilyHomologous superfamily
IPR035789 Rho guanine nucleotide exchange factor 7, SH3 domainDomainDomain
IPR035899 Dbl homology (DH) domain superfamilyFamilyHomologous superfamily
IPR036028 SH3-like domain superfamilyFamilyHomologous superfamily
IPR036872 CH domain superfamilyFamilyHomologous superfamily

Diseases

Show/Hide Table

Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
ARHG7_HUMANMBP_MOUSEBioGRID, MINT18067320 details