Entity Details

Primary name DCTN1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ14203
EntryNameDCTN1_HUMAN
FullNameDynactin subunit 1
TaxID9606
Evidenceevidence at protein level
Length1278
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesDCTN1

GO terms

Show/Hide Table
GOName
GO:0000086 G2/M transition of mitotic cell cycle
GO:0000132 establishment of mitotic spindle orientation
GO:0000278 mitotic cell cycle
GO:0000776 kinetochore
GO:0000922 spindle pole
GO:0005634 nucleus
GO:0005635 nuclear envelope
GO:0005737 cytoplasm
GO:0005813 centrosome
GO:0005814 centriole
GO:0005819 spindle
GO:0005829 cytosol
GO:0005874 microtubule
GO:0005875 microtubule associated complex
GO:0005938 cell cortex
GO:0006888 endoplasmic reticulum to Golgi vesicle-mediated transport
GO:0007097 nuclear migration
GO:0007399 nervous system development
GO:0007528 neuromuscular junction development
GO:0008017 microtubule binding
GO:0010389 regulation of G2/M transition of mitotic cell cycle
GO:0010457 centriole-centriole cohesion
GO:0015630 microtubule cytoskeleton
GO:0015631 tubulin binding
GO:0016020 membrane
GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0019901 protein kinase binding
GO:0021517 ventral spinal cord development
GO:0030286 dynein complex
GO:0030424 axon
GO:0031116 positive regulation of microtubule polymerization
GO:0031122 cytoplasmic microtubule organization
GO:0034454 microtubule anchoring at centrosome
GO:0035371 microtubule plus-end
GO:0036498 IRE1-mediated unfolded protein response
GO:0042147 retrograde transport, endosome to Golgi
GO:0043005 neuron projection
GO:0043025 neuronal cell body
GO:0045171 intercellular bridge
GO:0048156 tau protein binding
GO:0050905 neuromuscular process
GO:0051010 microtubule plus-end binding
GO:0051081 nuclear membrane disassembly
GO:0051301 cell division
GO:0060236 regulation of mitotic spindle organization
GO:0061744 motor behavior
GO:0070050 neuron cellular homeostasis
GO:0072686 mitotic spindle
GO:0090063 positive regulation of microtubule nucleation
GO:0097711 ciliary basal body-plasma membrane docking
GO:0099558 maintenance of synapse structure
GO:0099738 cell cortex region
GO:0120103 centriolar subdistal appendage
GO:1904398 positive regulation of neuromuscular junction development
GO:1905515 non-motile cilium assembly
GO:1990535 neuron projection maintenance

Subcellular Location

Show/Hide Table
Subcellular Location
Cytoplasm
Nucleus envelope

Domains

Show/Hide Table
DomainNameCategoryType
IPR000938 CAP Gly-rich domainDomainDomain
IPR022157 Dynein associated proteinDomainDomain
IPR036859 CAP Gly-rich domain superfamilyFamilyHomologous superfamily

Diseases

Show/Hide Table

Interactions

4 interactions