Entity Details

Primary name GRB7_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ14451
EntryNameGRB7_HUMAN
FullNameGrowth factor receptor-bound protein 7
TaxID9606
Evidenceevidence at protein level
Length532
SequenceStatuscomplete
DateCreated1999-07-15
DateModified2021-06-02

Ontological Relatives

GenesGRB7

GO terms

Show/Hide Table
GOName
GO:0003723 RNA binding
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0005925 focal adhesion
GO:0007173 epidermal growth factor receptor signaling pathway
GO:0007411 axon guidance
GO:0010494 cytoplasmic stress granule
GO:0017148 negative regulation of translation
GO:0019901 protein kinase binding
GO:0030335 positive regulation of cell migration
GO:0034063 stress granule assembly
GO:0035091 phosphatidylinositol binding
GO:0038128 ERBB2 signaling pathway
GO:0042802 identical protein binding
GO:0042995 cell projection
GO:0050900 leukocyte migration

Subcellular Location

Show/Hide Table
Subcellular Location
Cell junction
Cell membrane
Cell projection
Cytoplasm
Cytoplasmic granule

Domains

Show/Hide Table
DomainNameCategoryType
IPR000159 Ras-associating (RA) domainDomainDomain
IPR000980 SH2 domainDomainDomain
IPR001849 Pleckstrin homology domainDomainDomain
IPR011993 PH-like domain superfamilyFamilyHomologous superfamily
IPR015042 BPS (Between PH and SH2) domainDomainDomain
IPR029071 Ubiquitin-like domain superfamilyFamilyHomologous superfamily
IPR035032 Growth factor receptor-bound protein 7FamilyFamily
IPR036860 SH2 domain superfamilyFamilyHomologous superfamily
IPR039664 GRB/APBB1IPFamilyFamily
IPR039665 APBB1IP, PH domainDomainDomain

Diseases

Show/Hide Table

Interactions

4 interactions