Entity Details

Primary name MET_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP16056
EntryNameMET_MOUSE
FullNameHepatocyte growth factor receptor
TaxID10090
Evidenceevidence at protein level
Length1379
SequenceStatuscomplete
DateCreated1990-04-01
DateModified2021-04-07

Ontological Relatives

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000187 obsolete activation of MAPK activity
GO:0001764 neuron migration
GO:0001886 endothelial cell morphogenesis
GO:0001889 liver development
GO:0001890 placenta development
GO:0004672 protein kinase activity
GO:0004713 protein tyrosine kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0005008 hepatocyte growth factor-activated receptor activity
GO:0005524 ATP binding
GO:0005615 extracellular space
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0005887 integral component of plasma membrane
GO:0006909 phagocytosis
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007268 chemical synaptic transmission
GO:0007275 multicellular organism development
GO:0007399 nervous system development
GO:0007420 brain development
GO:0007517 muscle organ development
GO:0007519 skeletal muscle tissue development
GO:0008013 beta-catenin binding
GO:0009925 basal plasma membrane
GO:0010628 positive regulation of gene expression
GO:0010629 negative regulation of gene expression
GO:0010800 positive regulation of peptidyl-threonine phosphorylation
GO:0010801 negative regulation of peptidyl-threonine phosphorylation
GO:0010828 positive regulation of glucose transmembrane transport
GO:0010976 positive regulation of neuron projection development
GO:0014069 postsynaptic density
GO:0014812 muscle cell migration
GO:0014902 myotube differentiation
GO:0016020 membrane
GO:0016477 cell migration
GO:0017154 semaphorin receptor activity
GO:0019903 protein phosphatase binding
GO:0030182 neuron differentiation
GO:0030317 flagellated sperm motility
GO:0030425 dendrite
GO:0030534 adult behavior
GO:0031016 pancreas development
GO:0031116 positive regulation of microtubule polymerization
GO:0032675 regulation of interleukin-6 production
GO:0033138 positive regulation of peptidyl-serine phosphorylation
GO:0033674 positive regulation of kinase activity
GO:0035024 negative regulation of Rho protein signal transduction
GO:0036126 sperm flagellum
GO:0042593 glucose homeostasis
GO:0042802 identical protein binding
GO:0043005 neuron projection
GO:0043025 neuronal cell body
GO:0043235 receptor complex
GO:0043274 phospholipase binding
GO:0043548 phosphatidylinositol 3-kinase binding
GO:0044877 protein-containing complex binding
GO:0045211 postsynaptic membrane
GO:0045740 positive regulation of DNA replication
GO:0045840 positive regulation of mitotic nuclear division
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046777 protein autophosphorylation
GO:0048012 hepatocyte growth factor receptor signaling pathway
GO:0048754 branching morphogenesis of an epithelial tube
GO:0050775 positive regulation of dendrite morphogenesis
GO:0050804 modulation of chemical synaptic transmission
GO:0050918 positive chemotaxis
GO:0051450 myoblast proliferation
GO:0051497 negative regulation of stress fiber assembly
GO:0051897 positive regulation of protein kinase B signaling
GO:0055013 cardiac muscle cell development
GO:0060048 cardiac muscle contraction
GO:0060076 excitatory synapse
GO:0060079 excitatory postsynaptic potential
GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling
GO:0061436 establishment of skin barrier
GO:0070495 negative regulation of thrombin-activated receptor signaling pathway
GO:0071526 semaphorin-plexin signaling pathway
GO:0071635 negative regulation of transforming growth factor beta production
GO:0072593 reactive oxygen species metabolic process
GO:1900407 regulation of cellular response to oxidative stress
GO:1900745 positive regulation of p38MAPK cascade
GO:1901299 negative regulation of hydrogen peroxide-mediated programmed cell death
GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity
GO:2001028 positive regulation of endothelial cell chemotaxis

Subcellular Location

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Subcellular Location
Membrane

Domains

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DomainNameCategoryType
IPR000719 Protein kinase domainDomainDomain
IPR001245 Serine-threonine/tyrosine-protein kinase, catalytic domainDomainDomain
IPR001627 Sema domainDomainDomain
IPR002165 Plexin repeatRepeatRepeat
IPR002909 IPT domainDomainDomain
IPR008266 Tyrosine-protein kinase, active siteSiteActive site
IPR011009 Protein kinase-like domain superfamilyFamilyHomologous superfamily
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR014756 Immunoglobulin E-setFamilyHomologous superfamily
IPR015943 WD40/YVTN repeat-like-containing domain superfamilyFamilyHomologous superfamily
IPR016201 PSI domainDomainDomain
IPR016244 Tyrosine-protein kinase, HGF/MSP receptorFamilyFamily
IPR017441 Protein kinase, ATP binding siteSiteBinding site
IPR020635 Tyrosine-protein kinase, catalytic domainDomainDomain
IPR031148 Plexin familyFamilyFamily
IPR036352 Sema domain superfamilyFamilyHomologous superfamily

Diseases

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