Entity Details

Primary name TRIPC_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ14669
EntryNameTRIPC_HUMAN
FullNameE3 ubiquitin-protein ligase TRIP12
TaxID9606
Evidenceevidence at protein level
Length1992
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesTRIP12

GO terms

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GOName
GO:0000209 protein polyubiquitination
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005829 cytosol
GO:0006281 DNA repair
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0006974 cellular response to DNA damage stimulus
GO:0016607 nuclear speck
GO:0045995 regulation of embryonic development
GO:0046966 thyroid hormone receptor binding
GO:0061630 ubiquitin protein ligase activity
GO:1901315 negative regulation of histone H2A K63-linked ubiquitination
GO:2000779 regulation of double-strand break repair
GO:2000780 negative regulation of double-strand break repair

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR000569 HECT domainDomainDomain
IPR004170 WWE domainDomainDomain
IPR011989 Armadillo-like helicalFamilyHomologous superfamily
IPR016024 Armadillo-type foldFamilyHomologous superfamily
IPR035983 HECT, E3 ligase catalytic domainFamilyHomologous superfamily
IPR037197 WWE domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

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