Entity Details

Primary name PUM1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ14671
EntryNamePUM1_HUMAN
FullNamePumilio homolog 1
TaxID9606
Evidenceevidence at protein level
Length1186
SequenceStatuscomplete
DateCreated2004-02-02
DateModified2021-06-02

Ontological Relatives

GenesPUM1

GO terms

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GOName
GO:0000932 P-body
GO:0003723 RNA binding
GO:0003729 mRNA binding
GO:0003730 mRNA 3'-UTR binding
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006892 post-Golgi vesicle-mediated transport
GO:0007283 spermatogenesis
GO:0008344 adult locomotory behavior
GO:0010494 cytoplasmic stress granule
GO:0010608 posttranscriptional regulation of gene expression
GO:0016441 posttranscriptional gene silencing
GO:0035196 production of miRNAs involved in gene silencing by miRNA
GO:0035198 miRNA binding
GO:0043488 regulation of mRNA stability
GO:0048863 stem cell differentiation
GO:0051726 regulation of cell cycle
GO:0051983 regulation of chromosome segregation
GO:0060964 regulation of gene silencing by miRNA
GO:0061157 mRNA destabilization
GO:1900246 positive regulation of RIG-I signaling pathway
GO:2000637 positive regulation of gene silencing by miRNA

Subcellular Location

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Subcellular Location
Cytoplasm
Cytoplasmic granule

Domains

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DomainNameCategoryType
IPR001313 Pumilio RNA-binding repeatRepeatRepeat
IPR011989 Armadillo-like helicalFamilyHomologous superfamily
IPR016024 Armadillo-type foldFamilyHomologous superfamily
IPR033133 Pumilio homology domainDomainDomain
IPR033712 Pumilio, RNA binding domainDomainDomain

Diseases

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Interactions

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