Entity Details

Primary name LBR_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ14739
EntryNameLBR_HUMAN
FullNameDelta(14)-sterol reductase LBR
TaxID9606
Evidenceevidence at protein level
Length615
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesLBR

GO terms

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GOName
GO:0003677 DNA binding
GO:0003723 RNA binding
GO:0005521 lamin binding
GO:0005634 nucleus
GO:0005635 nuclear envelope
GO:0005637 nuclear inner membrane
GO:0005639 integral component of nuclear inner membrane
GO:0005737 cytoplasm
GO:0005789 endoplasmic reticulum membrane
GO:0006695 cholesterol biosynthetic process
GO:0007084 mitotic nuclear membrane reassembly
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0016126 sterol biosynthetic process
GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors
GO:0030223 neutrophil differentiation
GO:0031965 nuclear membrane
GO:0050613 delta14-sterol reductase activity
GO:0070087 chromo shadow domain binding
GO:0070402 NADPH binding

Subcellular Location

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Subcellular Location
Cytoplasm
Endoplasmic reticulum membrane
Nucleus
Nucleus inner membrane

Domains

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DomainNameCategoryType
IPR001171 Ergosterol biosynthesis ERG4/ERG24FamilyFamily
IPR002999 Tudor domainDomainDomain
IPR018083 Sterol reductase, conserved siteSiteConserved site
IPR019023 Lamin-B receptor of TUDOR domainDomainDomain

Diseases

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Interactions

0 interactions

InteractorPartnerSourcesPublicationsLink