Entity Details

Primary name BLK_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP16277
EntryNameBLK_MOUSE
FullNameTyrosine-protein kinase Blk
TaxID10090
Evidenceevidence at protein level
Length499
SequenceStatuscomplete
DateCreated1990-08-01
DateModified2021-06-02

Ontological Relatives

GenesBlk

GO terms

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GOName
GO:0002431 Fc receptor mediated stimulatory signaling pathway
GO:0002513 tolerance induction to self antigen
GO:0002576 platelet degranulation
GO:0002902 regulation of B cell apoptotic process
GO:0004713 protein tyrosine kinase activity
GO:0004714 transmembrane receptor protein tyrosine kinase activity
GO:0004715 non-membrane spanning protein tyrosine kinase activity
GO:0005102 signaling receptor binding
GO:0005524 ATP binding
GO:0005829 cytosol
GO:0006974 cellular response to DNA damage stimulus
GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
GO:0018108 peptidyl-tyrosine phosphorylation
GO:0030154 cell differentiation
GO:0030889 negative regulation of B cell proliferation
GO:0031175 neuron projection development
GO:0031234 extrinsic component of cytoplasmic side of plasma membrane
GO:0032024 positive regulation of insulin secretion
GO:0043304 regulation of mast cell degranulation
GO:0045087 innate immune response
GO:0050853 B cell receptor signaling pathway
GO:0050855 regulation of B cell receptor signaling pathway
GO:0070667 negative regulation of mast cell proliferation
GO:0090330 regulation of platelet aggregation
GO:0097028 dendritic cell differentiation
GO:2000670 positive regulation of dendritic cell apoptotic process

Subcellular Location

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Subcellular Location
Cell membrane

Domains

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DomainNameCategoryType
IPR000719 Protein kinase domainDomainDomain
IPR000980 SH2 domainDomainDomain
IPR001245 Serine-threonine/tyrosine-protein kinase, catalytic domainDomainDomain
IPR001452 SH3 domainDomainDomain
IPR011009 Protein kinase-like domain superfamilyFamilyHomologous superfamily
IPR017441 Protein kinase, ATP binding siteSiteBinding site
IPR020635 Tyrosine-protein kinase, catalytic domainDomainDomain
IPR035853 Tyrosine-protein kinase Blk, SH2 domainDomainDomain
IPR036028 SH3-like domain superfamilyFamilyHomologous superfamily
IPR036860 SH2 domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
BLK_MOUSEP85A_MOUSEMINT8395016 details
BLK_MOUSEPLCG2_MOUSEMINT8395016 details