Entity Details

Primary name IMB1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ14974
EntryNameIMB1_HUMAN
FullNameImportin subunit beta-1
TaxID9606
Evidenceevidence at protein level
Length876
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesKPNB1

GO terms

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GOName
GO:0003723 RNA binding
GO:0005576 extracellular region
GO:0005634 nucleus
GO:0005635 nuclear envelope
GO:0005643 nuclear pore
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006309 apoptotic DNA fragmentation
GO:0006606 protein import into nucleus
GO:0006607 NLS-bearing protein import into nucleus
GO:0006610 ribosomal protein import into nucleus
GO:0007079 mitotic chromosome movement towards spindle pole
GO:0007080 mitotic metaphase plate congression
GO:0007084 mitotic nuclear membrane reassembly
GO:0008139 nuclear localization sequence binding
GO:0008270 zinc ion binding
GO:0010494 cytoplasmic stress granule
GO:0016020 membrane
GO:0019054 modulation by virus of host cellular process
GO:0019899 enzyme binding
GO:0019904 protein domain specific binding
GO:0030953 astral microtubule organization
GO:0031267 small GTPase binding
GO:0031291 Ran protein signal transduction
GO:0031965 nuclear membrane
GO:0035580 specific granule lumen
GO:0040001 establishment of mitotic spindle localization
GO:0043312 neutrophil degranulation
GO:0043657 host cell
GO:0045184 establishment of protein localization
GO:0045540 regulation of cholesterol biosynthetic process
GO:0061608 nuclear import signal receptor activity
GO:0070062 extracellular exosome
GO:0071782 endoplasmic reticulum tubular network
GO:0075733 intracellular transport of virus
GO:0090307 mitotic spindle assembly
GO:1904813 ficolin-1-rich granule lumen

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus envelope

Domains

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DomainNameCategoryType
IPR000225 ArmadilloRepeatRepeat
IPR001494 Importin-beta, N-terminal domainDomainDomain
IPR011989 Armadillo-like helicalFamilyHomologous superfamily
IPR016024 Armadillo-type foldFamilyHomologous superfamily
IPR021133 HEAT, type 2RepeatRepeat
IPR040122 Importin beta familyFamilyFamily

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
IMB1_HUMANMRTFA_MOUSEMINT20818336 details
IMB1_HUMANOSTM1_MOUSEBioGRID26598607 details