Entity Details

Primary name NR1D2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ14995
EntryNameNR1D2_HUMAN
FullNameNuclear receptor subfamily 1 group D member 2
TaxID9606
Evidenceevidence at protein level
Length579
SequenceStatuscomplete
DateCreated1999-07-15
DateModified2021-06-02

Ontological Relatives

GenesNR1D2

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0001227 DNA-binding transcription repressor activity, RNA polymerase II-specific
GO:0004879 nuclear receptor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0006355 regulation of transcription, DNA-templated
GO:0006367 transcription initiation from RNA polymerase II promoter
GO:0008270 zinc ion binding
GO:0009755 hormone-mediated signaling pathway
GO:0019216 regulation of lipid metabolic process
GO:0030154 cell differentiation
GO:0042752 regulation of circadian rhythm
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048512 circadian behavior
GO:0050727 regulation of inflammatory response
GO:0050728 negative regulation of inflammatory response
GO:0055088 lipid homeostasis
GO:0097009 energy homeostasis
GO:1990837 sequence-specific double-stranded DNA binding
GO:2001014 regulation of skeletal muscle cell differentiation

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR000536 Nuclear hormone receptor, ligand-binding domainDomainDomain
IPR001628 Zinc finger, nuclear hormone receptor-typeDomainDomain
IPR001723 Nuclear hormone receptorFamilyFamily
IPR013088 Zinc finger, NHR/GATA-typeFamilyHomologous superfamily
IPR035500 Nuclear hormone receptor-like domain superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB14013 SR-9009Drugbanksmall molecule
DB14014 SR-9011Drugbanksmall molecule

Interactions

3 interactions