Entity Details

Primary name PSMD6_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ15008
EntryNamePSMD6_HUMAN
FullName26S proteasome non-ATPase regulatory subunit 6
TaxID9606
Evidenceevidence at protein level
Length389
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesPSMD6

GO terms

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GOName
GO:0000165 MAPK cascade
GO:0000209 protein polyubiquitination
GO:0000502 proteasome complex
GO:0002223 stimulatory C-type lectin receptor signaling pathway
GO:0002479 antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0005576 extracellular region
GO:0005654 nucleoplasm
GO:0005829 cytosol
GO:0005838 proteasome regulatory particle
GO:0006508 proteolysis
GO:0006521 regulation of cellular amino acid metabolic process
GO:0010972 negative regulation of G2/M transition of mitotic cell cycle
GO:0016579 protein deubiquitination
GO:0016887 ATP hydrolysis activity
GO:0022624 proteasome accessory complex
GO:0030234 enzyme regulator activity
GO:0031145 anaphase-promoting complex-dependent catabolic process
GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0033209 tumor necrosis factor-mediated signaling pathway
GO:0034774 secretory granule lumen
GO:0036388 pre-replicative complex assembly
GO:0038061 NIK/NF-kappaB signaling
GO:0038095 Fc-epsilon receptor signaling pathway
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0043312 neutrophil degranulation
GO:0043488 regulation of mRNA stability
GO:0043687 post-translational protein modification
GO:0050852 T cell receptor signaling pathway
GO:0055085 transmembrane transport
GO:0060071 Wnt signaling pathway, planar cell polarity pathway
GO:0061418 regulation of transcription from RNA polymerase II promoter in response to hypoxia
GO:0070498 interleukin-1-mediated signaling pathway
GO:0090090 negative regulation of canonical Wnt signaling pathway
GO:0090263 positive regulation of canonical Wnt signaling pathway
GO:1901990 regulation of mitotic cell cycle phase transition
GO:1902036 regulation of hematopoietic stem cell differentiation
GO:1904813 ficolin-1-rich granule lumen

Subcellular Location

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Domains

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DomainNameCategoryType
IPR000717 Proteasome component (PCI) domainDomainDomain
IPR011990 Tetratricopeptide-like helical domain superfamilyFamilyHomologous superfamily
IPR019585 26S proteasome regulatory subunit Rpn7/COP9 signalosome complex subunit 1FamilyFamily
IPR035268 26S Proteasome non-ATPase regulatory subunit 6FamilyFamily
IPR036390 Winged helix DNA-binding domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

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