Entity Details - PICKLE: A Protein InteraCtion KnowLedgebasE

Genes

KARS1

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GO	Name
GO:0000049	tRNA binding
GO:0002276	basophil activation involved in immune response
GO:0002863	positive regulation of inflammatory response to antigenic stimulus
GO:0003877	ATP adenylyltransferase activity
GO:0004824	lysine-tRNA ligase activity
GO:0005524	ATP binding
GO:0005615	extracellular space
GO:0005634	nucleus
GO:0005739	mitochondrion
GO:0005759	mitochondrial matrix
GO:0005829	cytosol
GO:0005886	plasma membrane
GO:0006418	tRNA aminoacylation for protein translation
GO:0006430	lysyl-tRNA aminoacylation
GO:0008033	tRNA processing
GO:0010165	response to X-ray
GO:0015966	diadenosine tetraphosphate biosynthetic process
GO:0016032	viral process
GO:0016597	amino acid binding
GO:0017101	aminoacyl-tRNA synthetase multienzyme complex
GO:0042802	identical protein binding
GO:0042803	protein homodimerization activity
GO:0043032	positive regulation of macrophage activation
GO:0045893	positive regulation of transcription, DNA-templated
GO:0070371	ERK1 and ERK2 cascade

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Domain	Name	Category	Type
IPR002313	Lysine-tRNA ligase, class II	Family	Family
IPR004364	Aminoacyl-tRNA synthetase, class II (D/K/N)	Domain	Domain
IPR004365	OB-fold nucleic acid binding domain, AA-tRNA synthetase-type	Domain	Domain
IPR006195	Aminoacyl-tRNA synthetase, class II	Domain	Domain
IPR012340	Nucleic acid-binding, OB-fold	Family	Homologous superfamily
IPR018149	Lysyl-tRNA synthetase, class II, C-terminal	Domain	Domain
IPR034762	Bacterial/eukaryotic lysine-tRNA ligase, class II	Family	Family
IPR044136	Lysine-tRNA ligase, class II, N-terminal	Domain	Domain

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Drug	Name	Source	Type
DB00123	L-Lysine	Drugbank	small molecule

0 interactions

Interactor	Partner	Sources	Publications	Link