Entity Details

Primary name EEA1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ15075
EntryNameEEA1_HUMAN
FullNameEarly endosome antigen 1
TaxID9606
Evidenceevidence at protein level
Length1411
SequenceStatuscomplete
DateCreated2003-08-22
DateModified2021-06-02

Ontological Relatives

GenesEEA1

GO terms

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GOName
GO:0005516 calmodulin binding
GO:0005545 1-phosphatidylinositol binding
GO:0005737 cytoplasm
GO:0005769 early endosome
GO:0005829 cytosol
GO:0005969 serine-pyruvate aminotransferase complex
GO:0006897 endocytosis
GO:0006906 vesicle fusion
GO:0008270 zinc ion binding
GO:0016020 membrane
GO:0016189 synaptic vesicle to endosome fusion
GO:0019897 extrinsic component of plasma membrane
GO:0030742 GTP-dependent protein binding
GO:0031901 early endosome membrane
GO:0039694 viral RNA genome replication
GO:0042803 protein homodimerization activity
GO:0044308 axonal spine
GO:0045022 early endosome to late endosome transport
GO:0055037 recycling endosome
GO:0070062 extracellular exosome

Subcellular Location

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Subcellular Location
Cytoplasm
Early endosome membrane

Domains

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DomainNameCategoryType
IPR000306 FYVE zinc fingerDomainDomain
IPR011011 Zinc finger, FYVE/PHD-typeFamilyHomologous superfamily
IPR013083 Zinc finger, RING/FYVE/PHD-typeFamilyHomologous superfamily
IPR013087 Zinc finger C2H2-typeDomainDomain
IPR017455 Zinc finger, FYVE-relatedDomainDomain

Diseases

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Drugs

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DrugNameSourceType
DB02942 Inositol 1,3-BisphosphateDrugbanksmall molecule

Interactions

3 interactions