Entity Details

Primary name CD5R1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ15078
EntryNameCD5R1_HUMAN
FullNameCyclin-dependent kinase 5 activator 1
TaxID9606
Evidenceevidence at protein level
Length307
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesCDK5R1

GO terms

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GOName
GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0000226 microtubule cytoskeleton organization
GO:0001764 neuron migration
GO:0002020 protease binding
GO:0004672 protein kinase activity
GO:0005509 calcium ion binding
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0007158 neuron cell-cell adhesion
GO:0007213 G protein-coupled acetylcholine receptor signaling pathway
GO:0007411 axon guidance
GO:0007413 axonal fasciculation
GO:0007420 brain development
GO:0009792 embryo development ending in birth or egg hatching
GO:0014069 postsynaptic density
GO:0016020 membrane
GO:0016241 regulation of macroautophagy
GO:0016301 kinase activity
GO:0016533 protein kinase 5 complex
GO:0018105 peptidyl-serine phosphorylation
GO:0018107 peptidyl-threonine phosphorylation
GO:0019901 protein kinase binding
GO:0021549 cerebellum development
GO:0021722 superior olivary nucleus maturation
GO:0021766 hippocampus development
GO:0021819 layer formation in cerebral cortex
GO:0030182 neuron differentiation
GO:0030295 protein kinase activator activity
GO:0030424 axon
GO:0030425 dendrite
GO:0030426 growth cone
GO:0030517 negative regulation of axon extension
GO:0031116 positive regulation of microtubule polymerization
GO:0031175 neuron projection development
GO:0031594 neuromuscular junction
GO:0032956 regulation of actin cytoskeleton organization
GO:0035235 ionotropic glutamate receptor signaling pathway
GO:0035255 ionotropic glutamate receptor binding
GO:0042501 serine phosphorylation of STAT protein
GO:0043005 neuron projection
GO:0043014 alpha-tubulin binding
GO:0043025 neuronal cell body
GO:0043197 dendritic spine
GO:0043204 perikaryon
GO:0043231 intracellular membrane-bounded organelle
GO:0043292 contractile fiber
GO:0043525 positive regulation of neuron apoptotic process
GO:0043539 protein serine/threonine kinase activator activity
GO:0045296 cadherin binding
GO:0045348 positive regulation of MHC class II biosynthetic process
GO:0045664 regulation of neuron differentiation
GO:0045892 negative regulation of transcription, DNA-templated
GO:0046875 ephrin receptor binding
GO:0048013 ephrin receptor signaling pathway
GO:0048471 perinuclear region of cytoplasm
GO:0048487 beta-tubulin binding
GO:0048511 rhythmic process
GO:0051015 actin filament binding
GO:0061001 regulation of dendritic spine morphogenesis
GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity
GO:0090314 positive regulation of protein targeting to membrane
GO:0098693 regulation of synaptic vesicle cycle
GO:0098793 presynapse
GO:1901796 regulation of signal transduction by p53 class mediator
GO:2000273 positive regulation of signaling receptor activity

Subcellular Location

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Subcellular Location
Cell membrane
Cell projection
Cytoplasm
Nucleus
Perikaryon

Domains

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DomainNameCategoryType
IPR004944 Cyclin-dependent kinase 5 activatorFamilyFamily
IPR036915 Cyclin-like superfamilyFamilyHomologous superfamily

Diseases

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Drugs

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DrugNameSourceType
DB02052 Indirubin-3'-monoximeDrugbanksmall molecule
DB07364 6-PHENYL[5H]PYRROLO[2,3-B]PYRAZINEDrugbanksmall molecule

Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
CD5R1_HUMANCOR1A_MOUSEMINT26823173 details
CD5R1_HUMANSDS3_MOUSEBioGRID15489224 details