Entity Details

Primary name KCNA1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP16388
EntryNameKCNA1_MOUSE
FullNamePotassium voltage-gated channel subfamily A member 1
TaxID10090
Evidenceevidence at protein level
Length495
SequenceStatuscomplete
DateCreated1990-08-01
DateModified2021-06-02

Ontological Relatives

GenesKcna1

GO terms

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GOName
GO:0001964 startle response
GO:0005249 voltage-gated potassium channel activity
GO:0005251 delayed rectifier potassium channel activity
GO:0005783 endoplasmic reticulum
GO:0005829 cytosol
GO:0005887 integral component of plasma membrane
GO:0006937 regulation of muscle contraction
GO:0007405 neuroblast proliferation
GO:0007420 brain development
GO:0008076 voltage-gated potassium channel complex
GO:0009986 cell surface
GO:0010644 cell communication by electrical coupling
GO:0010960 magnesium ion homeostasis
GO:0016021 integral component of membrane
GO:0016324 apical plasma membrane
GO:0019228 neuronal action potential
GO:0021766 hippocampus development
GO:0023041 neuronal signal transduction
GO:0030054 cell junction
GO:0030424 axon
GO:0030425 dendrite
GO:0031410 cytoplasmic vesicle
GO:0033270 paranode region of axon
GO:0034613 cellular protein localization
GO:0034705 potassium channel complex
GO:0042391 regulation of membrane potential
GO:0042734 presynaptic membrane
GO:0043025 neuronal cell body
GO:0043204 perikaryon
GO:0043679 axon terminus
GO:0044224 juxtaparanode region of axon
GO:0044305 calyx of Held
GO:0045202 synapse
GO:0050905 neuromuscular process
GO:0050966 detection of mechanical stimulus involved in sensory perception of pain
GO:0050976 detection of mechanical stimulus involved in sensory perception of touch
GO:0051260 protein homooligomerization
GO:0071286 cellular response to magnesium ion
GO:0071805 potassium ion transmembrane transport
GO:0097718 disordered domain specific binding
GO:0098978 glutamatergic synapse
GO:0099055 integral component of postsynaptic membrane
GO:0099056 integral component of presynaptic membrane
GO:0099508 voltage-gated ion channel activity involved in regulation of presynaptic membrane potential
GO:1903818 positive regulation of voltage-gated potassium channel activity
GO:1905030 voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential

Subcellular Location

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Subcellular Location
Cell junction
Cell membrane
Cell projection
Cytoplasmic vesicle
Endoplasmic reticulum
Membrane
Perikaryon

Domains

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DomainNameCategoryType
IPR000210 BTB/POZ domainDomainDomain
IPR003131 Potassium channel tetramerisation-type BTB domainDomainDomain
IPR003968 Potassium channel, voltage dependent, KvFamilyFamily
IPR003972 Potassium channel, voltage dependent, Kv1FamilyFamily
IPR004048 Potassium channel, voltage dependent, Kv1.1FamilyFamily
IPR005821 Ion transport domainDomainDomain
IPR011333 SKP1/BTB/POZ domain superfamilyFamilyHomologous superfamily
IPR027359 Voltage-dependent channel domain superfamilyFamilyHomologous superfamily
IPR028325 Voltage-gated potassium channelFamilyFamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
KCNA1_MOUSEKCNA2_MOUSEBioGRID18053989 details