Entity Details

Primary name PTPRR_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ15256
EntryNamePTPRR_HUMAN
FullNameReceptor-type tyrosine-protein phosphatase R
TaxID9606
Evidenceevidence at protein level
Length657
SequenceStatuscomplete
DateCreated2002-11-15
DateModified2021-06-02

Ontological Relatives

GenesPTPRR

GO terms

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GOName
GO:0001701 in utero embryonic development
GO:0004725 protein tyrosine phosphatase activity
GO:0005001 transmembrane receptor protein tyrosine phosphatase activity
GO:0005615 extracellular space
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006470 protein dephosphorylation
GO:0010633 negative regulation of epithelial cell migration
GO:0016021 integral component of membrane
GO:0019901 protein kinase binding
GO:0030054 cell junction
GO:0038128 ERBB2 signaling pathway
GO:0048471 perinuclear region of cytoplasm
GO:0070373 negative regulation of ERK1 and ERK2 cascade

Subcellular Location

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Subcellular Location
Cell membrane
Cytoplasm

Domains

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DomainNameCategoryType
IPR000242 PTP type protein phosphataseDomainDomain
IPR000387 Tyrosine specific protein phosphatases domainDomainDomain
IPR003595 Protein-tyrosine phosphatase, catalyticDomainDomain
IPR008356 Protein-tyrosine phosphatase, KIM-containingFamilyFamily
IPR016130 Protein-tyrosine phosphatase, active siteSiteActive site
IPR016334 Protein-tyrosine phosphatase, receptor type R/non-receptor type 5FamilyFamily
IPR029021 Protein-tyrosine phosphatase-likeFamilyHomologous superfamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
PTPRR_HUMANRON_MOUSEMINT28065597 details