Entity Details

Primary name NHRF2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ15599
EntryNameNHRF2_HUMAN
FullNameNa(+)/H(+) exchange regulatory cofactor NHE-RF2
TaxID9606
Evidenceevidence at protein level
Length337
SequenceStatuscomplete
DateCreated2004-02-16
DateModified2021-06-02

Ontological Relatives

GenesSLC9A3R2

GO terms

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GOName
GO:0005102 signaling receptor binding
GO:0005634 nucleus
GO:0005886 plasma membrane
GO:0005925 focal adhesion
GO:0008013 beta-catenin binding
GO:0008022 protein C-terminus binding
GO:0012505 endomembrane system
GO:0016324 apical plasma membrane
GO:0019902 phosphatase binding
GO:0031799 type 2 metabotropic glutamate receptor binding
GO:0031800 type 3 metabotropic glutamate receptor binding
GO:0042802 identical protein binding
GO:0043495 protein-membrane adaptor activity
GO:0045296 cadherin binding
GO:0065003 protein-containing complex assembly
GO:0070062 extracellular exosome
GO:0072659 protein localization to plasma membrane

Subcellular Location

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Subcellular Location
Apical cell membrane
Endomembrane system
Nucleus

Domains

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DomainNameCategoryType
IPR001478 PDZ domainDomainDomain
IPR015098 EBP50, C-terminalDomainDomain
IPR017300 Na(+)/H(+) exchange regulatory cofactor NHERF-1/2FamilyFamily
IPR031197 Na(+)/H(+) exchange regulatory cofactor NHERF-2FamilyFamily
IPR036034 PDZ superfamilyFamilyHomologous superfamily

Diseases

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Interactions

5 interactions