Entity Details

Primary name IL7RA_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP16872
EntryNameIL7RA_MOUSE
FullNameInterleukin-7 receptor subunit alpha
TaxID10090
Evidenceevidence at protein level
Length459
SequenceStatuscomplete
DateCreated1990-08-01
DateModified2021-06-02

Ontological Relatives

GenesIl7r

GO terms

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GOName
GO:0000902 cell morphogenesis
GO:0001915 negative regulation of T cell mediated cytotoxicity
GO:0004896 cytokine receptor activity
GO:0005654 nucleoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0008284 positive regulation of cell population proliferation
GO:0008361 regulation of cell size
GO:0009897 external side of plasma membrane
GO:0010628 positive regulation of gene expression
GO:0016021 integral component of membrane
GO:0030217 T cell differentiation
GO:0033089 positive regulation of T cell differentiation in thymus
GO:0042100 B cell proliferation
GO:0048535 lymph node development
GO:0048872 homeostasis of number of cells
GO:0050830 defense response to Gram-positive bacterium
GO:0070233 negative regulation of T cell apoptotic process
GO:1904894 positive regulation of receptor signaling pathway via STAT

Subcellular Location

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Subcellular Location
Membrane

Domains

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DomainNameCategoryType
IPR003531 Short hematopoietin receptor, family 1, conserved siteSiteConserved site
IPR003961 Fibronectin type IIIDomainDomain
IPR013783 Immunoglobulin-like foldFamilyHomologous superfamily
IPR036116 Fibronectin type III superfamilyFamilyHomologous superfamily
IPR040997 IL-7Ralpha, fibronectin type III domainDomainDomain

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
IL7RA_MOUSETSLP_MOUSEDIP24632570 details
IL7RA_MOUSEJAK1_MOUSEDIP20974963 details