Entity Details

Primary name DLG2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ15700
EntryNameDLG2_HUMAN
FullNameDisks large homolog 2
TaxID9606
Evidenceevidence at protein level
Length870
SequenceStatuscomplete
DateCreated1997-11-01
DateModified2021-06-02

Ontological Relatives

GenesDLG2

GO terms

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GOName
GO:0005886 plasma membrane
GO:0014069 postsynaptic density
GO:0030054 cell junction
GO:0035865 cellular response to potassium ion
GO:0043005 neuron projection
GO:0044224 juxtaparanode region of axon
GO:0098609 cell-cell adhesion
GO:0000165 MAPK cascade
GO:0005829 cytosol
GO:0010923 negative regulation of phosphatase activity
GO:0019900 kinase binding
GO:0031594 neuromuscular junction
GO:0043113 receptor clustering
GO:1904115 axon cytoplasm
GO:0004385 guanylate kinase activity
GO:0007268 chemical synaptic transmission
GO:0016020 membrane
GO:0099642 retrograde axonal protein transport
GO:0016323 basolateral plasma membrane
GO:0043204 perikaryon
GO:0045197 establishment or maintenance of epithelial cell apical/basal polarity
GO:0097120 receptor localization to synapse
GO:0098839 postsynaptic density membrane
GO:0099641 anterograde axonal protein transport
GO:2000310 regulation of NMDA receptor activity

Subcellular Location

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Subcellular Location
Cell junction
Cell membrane
Cell projection
Membrane
Perikaryon

Domains

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DomainNameCategoryType
IPR001452 SH3 domainDomainDomain
IPR001478 PDZ domainDomainDomain
IPR008144 Guanylate kinase-like domainDomainDomain
IPR008145 Guanylate kinase/L-type calcium channel beta subunitDomainDomain
IPR016313 Disks large 1-likeFamilyFamily
IPR019583 PDZ-associated domain of NMDA receptorsDomainDomain
IPR019590 Disks large homologue 1, N-terminal PEST domainDomainDomain
IPR020590 Guanylate kinase, conserved siteSiteConserved site
IPR027417 P-loop containing nucleoside triphosphate hydrolaseFamilyHomologous superfamily
IPR035759 Disks Large homologue 2, SH3 domainDomainDomain
IPR036028 SH3-like domain superfamilyFamilyHomologous superfamily
IPR036034 PDZ superfamilyFamilyHomologous superfamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
DLG2_HUMANKCNJ2_MOUSEIntAct15304517 details