Entity Details

Primary name ATF2_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP16951
EntryNameATF2_MOUSE
FullNameCyclic AMP-dependent transcription factor ATF-2
TaxID10090
Evidenceevidence at protein level
Length487
SequenceStatuscomplete
DateCreated1990-08-01
DateModified2021-06-02

Ontological Relatives

GenesAtf2

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000785 chromatin
GO:0000977 RNA polymerase II transcription regulatory region sequence-specific DNA binding
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0000987 cis-regulatory region sequence-specific DNA binding
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0003151 outflow tract morphogenesis
GO:0003677 DNA binding
GO:0003682 chromatin binding
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005741 mitochondrial outer membrane
GO:0006355 regulation of transcription, DNA-templated
GO:0006357 regulation of transcription by RNA polymerase II
GO:0006970 response to osmotic stress
GO:0006974 cellular response to DNA damage stimulus
GO:0008134 transcription factor binding
GO:0008140 cAMP response element binding protein binding
GO:0009414 response to water deprivation
GO:0010485 H4 histone acetyltransferase activity
GO:0010628 positive regulation of gene expression
GO:0016020 membrane
GO:0016525 negative regulation of angiogenesis
GO:0019901 protein kinase binding
GO:0031573 mitotic intra-S DNA damage checkpoint signaling
GO:0032915 positive regulation of transforming growth factor beta2 production
GO:0035497 cAMP response element binding
GO:0035861 site of double-strand break
GO:0043525 positive regulation of neuron apoptotic process
GO:0043565 sequence-specific DNA binding
GO:0043967 histone H4 acetylation
GO:0043969 histone H2B acetylation
GO:0044013 H2B histone acetyltransferase activity
GO:0044877 protein-containing complex binding
GO:0045444 fat cell differentiation
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046872 metal ion binding
GO:0050680 negative regulation of epithelial cell proliferation
GO:0051091 positive regulation of DNA-binding transcription factor activity
GO:0060612 adipose tissue development
GO:0097186 amelogenesis
GO:0110024 positive regulation of cardiac muscle myoblast proliferation
GO:1902110 positive regulation of mitochondrial membrane permeability involved in apoptotic process
GO:1902562 H4 histone acetyltransferase complex
GO:1990837 sequence-specific double-stranded DNA binding

Subcellular Location

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Subcellular Location
Cytoplasm
Mitochondrion outer membrane
Nucleus

Domains

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DomainNameCategoryType
IPR004827 Basic-leucine zipper domainDomainDomain
IPR013087 Zinc finger C2H2-typeDomainDomain
IPR016378 Transcription factor cyclic AMP-dependent, CRE-BP1-typeFamilyFamily
IPR029836 cAMP-dependent transcription factor ATF-2FamilyFamily
IPR036236 Zinc finger C2H2 superfamilyFamilyHomologous superfamily

Diseases

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