Entity Details

Primary name HMGA1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP17095
EntryNameHMGA1_MOUSE
FullNameHigh mobility group protein HMG-I/HMG-Y
TaxID10090
Evidenceevidence at protein level
Length107
SequenceStatuscomplete
DateCreated1990-08-01
DateModified2021-06-02

Ontological Relatives

GO terms

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GOName
GO:0000987 cis-regulatory region sequence-specific DNA binding
GO:0003677 DNA binding
GO:0003680 minor groove of adenine-thymine-rich DNA binding
GO:0003682 chromatin binding
GO:0003712 transcription coregulator activity
GO:0003713 transcription coactivator activity
GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity
GO:0005634 nucleus
GO:0006355 regulation of transcription, DNA-templated
GO:0007283 spermatogenesis
GO:0008134 transcription factor binding
GO:0008285 negative regulation of cell population proliferation
GO:0019899 enzyme binding
GO:0030374 nuclear receptor coactivator activity
GO:0030527 structural constituent of chromatin
GO:0035985 senescence-associated heterochromatin focus
GO:0035986 senescence-associated heterochromatin focus assembly
GO:0042974 retinoic acid receptor binding
GO:0042975 peroxisome proliferator activated receptor binding
GO:0045892 negative regulation of transcription, DNA-templated
GO:0045893 positive regulation of transcription, DNA-templated
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0046965 retinoid X receptor binding
GO:0051575 5'-deoxyribose-5-phosphate lyase activity
GO:0090402 oncogene-induced cell senescence
GO:0090575 RNA polymerase II transcription regulator complex
GO:2000774 positive regulation of cellular senescence

Subcellular Location

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Subcellular Location
Chromosome
Nucleus

Domains

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DomainNameCategoryType
IPR000116 High mobility group protein HMGAFamilyFamily
IPR000637 HMG-I/HMG-Y, DNA-binding, conserved siteSiteConserved site
IPR017956 AT hook, DNA-binding motifSiteConserved site
IPR031079 High mobility group protein HMG-I/HMG-Y, chordatesFamilyFamily

Diseases

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