Entity Details

Primary name PTBP1_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP17225
EntryNamePTBP1_MOUSE
FullNamePolypyrimidine tract-binding protein 1
TaxID10090
Evidenceevidence at protein level
Length527
SequenceStatuscomplete
DateCreated1990-08-01
DateModified2021-06-02

Ontological Relatives

GO terms

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GOName
GO:0000014 single-stranded DNA endodeoxyribonuclease activity
GO:0000381 regulation of alternative mRNA splicing, via spliceosome
GO:0000956 nuclear-transcribed mRNA catabolic process
GO:0001069 regulatory region RNA binding
GO:0003697 single-stranded DNA binding
GO:0003729 mRNA binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0006397 mRNA processing
GO:0008380 RNA splicing
GO:0010467 gene expression
GO:0010976 positive regulation of neuron projection development
GO:0022008 neurogenesis
GO:0032024 positive regulation of insulin secretion
GO:0033119 negative regulation of RNA splicing
GO:0035307 positive regulation of protein dephosphorylation
GO:0036002 pre-mRNA binding
GO:0043484 regulation of RNA splicing
GO:0043565 sequence-specific DNA binding
GO:0044306 neuron projection terminus
GO:0045595 regulation of cell differentiation
GO:0045665 negative regulation of neuron differentiation
GO:0045727 positive regulation of translation
GO:0045944 positive regulation of transcription by RNA polymerase II
GO:0048025 negative regulation of mRNA splicing, via spliceosome
GO:0051148 negative regulation of muscle cell differentiation
GO:0070886 positive regulation of calcineurin-NFAT signaling cascade
GO:0070935 3'-UTR-mediated mRNA stabilization
GO:0075522 IRES-dependent viral translational initiation
GO:1904411 positive regulation of secretory granule organization

Subcellular Location

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Subcellular Location
Nucleus

Domains

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DomainNameCategoryType
IPR000504 RNA recognition motif domainDomainDomain
IPR006536 HnRNP-L/PTBFamilyFamily
IPR012677 Nucleotide-binding alpha-beta plait domain superfamilyFamilyHomologous superfamily
IPR021790 PTBP1, RNA recognition motif 2-likeDomainDomain
IPR034798 Polypyrimidine tract-binding protein1/2/3, RNA recognition motif 2DomainDomain
IPR035000 PTBP1, RNA recognition motif 1DomainDomain
IPR035979 RNA-binding domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
PTBP1_MOUSEPA2G4_MOUSEMINT17690690 details
PTBP1_MOUSERAVR1_MOUSEMINT17690690 details