Entity Details

Primary name DDB1_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ16531
EntryNameDDB1_HUMAN
FullNameDNA damage-binding protein 1
TaxID9606
Evidenceevidence at protein level
Length1140
SequenceStatuscomplete
DateCreated2001-01-11
DateModified2021-06-02

Ontological Relatives

GenesDDB1

GO terms

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GOName
GO:0000715 nucleotide-excision repair, DNA damage recognition
GO:0000717 nucleotide-excision repair, DNA duplex unwinding
GO:0000781 chromosome, telomeric region
GO:0003677 DNA binding
GO:0003684 damaged DNA binding
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0006281 DNA repair
GO:0006283 transcription-coupled nucleotide-excision repair
GO:0006289 nucleotide-excision repair
GO:0006293 nucleotide-excision repair, preincision complex stabilization
GO:0006294 nucleotide-excision repair, preincision complex assembly
GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion
GO:0006296 nucleotide-excision repair, DNA incision, 5'-to lesion
GO:0006511 ubiquitin-dependent protein catabolic process
GO:0006974 cellular response to DNA damage stimulus
GO:0010498 proteasomal protein catabolic process
GO:0016032 viral process
GO:0016567 protein ubiquitination
GO:0030674 protein-macromolecule adaptor activity
GO:0031464 Cul4A-RING E3 ubiquitin ligase complex
GO:0031465 Cul4B-RING E3 ubiquitin ligase complex
GO:0032991 protein-containing complex
GO:0033683 nucleotide-excision repair, DNA incision
GO:0035518 histone H2A monoubiquitination
GO:0035861 site of double-strand break
GO:0042769 DNA damage response, detection of DNA damage
GO:0043161 proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0043687 post-translational protein modification
GO:0044877 protein-containing complex binding
GO:0045070 positive regulation of viral genome replication
GO:0045722 positive regulation of gluconeogenesis
GO:0045732 positive regulation of protein catabolic process
GO:0046726 positive regulation by virus of viral protein levels in host cell
GO:0048511 rhythmic process
GO:0051702 biological process involved in interaction with symbiont
GO:0070062 extracellular exosome
GO:0070911 global genome nucleotide-excision repair
GO:0070914 UV-damage excision repair
GO:0071987 WD40-repeat domain binding
GO:0080008 Cul4-RING E3 ubiquitin ligase complex
GO:0097602 cullin family protein binding
GO:1901990 regulation of mitotic cell cycle phase transition
GO:1902188 positive regulation of viral release from host cell

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR004871 Cleavage/polyadenylation specificity factor, A subunit, C-terminalDomainDomain
IPR015943 WD40/YVTN repeat-like-containing domain superfamilyFamilyHomologous superfamily
IPR018846 Cleavage/polyadenylation specificity factor, A subunit, N-terminalDomainDomain
IPR031297 DNA damage-binding protein 1FamilyFamily
IPR036322 WD40-repeat-containing domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

4 interactions