Entity Details

Primary name NFE2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ16621
EntryNameNFE2_HUMAN
FullNameTranscription factor NF-E2 45 kDa subunit
TaxID9606
Evidenceevidence at protein level
Length373
SequenceStatuscomplete
DateCreated2000-05-30
DateModified2021-06-02

Ontological Relatives

GenesNFE2

GO terms

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GOName
GO:0000785 chromatin
GO:0000978 RNA polymerase II cis-regulatory region sequence-specific DNA binding
GO:0000981 DNA-binding transcription factor activity, RNA polymerase II-specific
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0006337 nucleosome disassembly
GO:0006357 regulation of transcription by RNA polymerase II
GO:0007275 multicellular organism development
GO:0007596 blood coagulation
GO:0007599 hemostasis
GO:0016605 PML body
GO:0032993 protein-DNA complex
GO:0043565 sequence-specific DNA binding
GO:0045652 regulation of megakaryocyte differentiation
GO:0045893 positive regulation of transcription, DNA-templated
GO:0047485 protein N-terminus binding
GO:0050699 WW domain binding
GO:1990837 sequence-specific double-stranded DNA binding

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR004826 Basic leucine zipper domain, Maf-typeDomainDomain
IPR004827 Basic-leucine zipper domainDomainDomain
IPR008917 Transcription factor, Skn-1-like, DNA-binding domain superfamilyFamilyHomologous superfamily
IPR029853 Transcription factor NF-E2, 45kDa subunitFamilyFamily

Diseases

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Interactions

2 interactions

InteractorPartnerSourcesPublicationsLink
NFE2_HUMANNEDD4_MOUSEBioGRID9305852 details
NFE2_HUMANYAP1_MOUSEBioGRID9305852 details