Entity Details

Primary name PPIA_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP17742
EntryNamePPIA_MOUSE
FullNamePeptidyl-prolyl cis-trans isomerase A
TaxID10090
Evidenceevidence at protein level
Length164
SequenceStatuscomplete
DateCreated1990-08-01
DateModified2021-06-02

Ontological Relatives

GenesPpia

GO terms

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GOName
GO:0000187 obsolete activation of MAPK activity
GO:0000413 protein peptidyl-prolyl isomerization
GO:0001933 negative regulation of protein phosphorylation
GO:0001934 positive regulation of protein phosphorylation
GO:0003755 peptidyl-prolyl cis-trans isomerase activity
GO:0005178 integrin binding
GO:0005576 extracellular region
GO:0005615 extracellular space
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0006457 protein folding
GO:0006469 negative regulation of protein kinase activity
GO:0006915 apoptotic process
GO:0016018 cyclosporin A binding
GO:0030168 platelet activation
GO:0030182 neuron differentiation
GO:0030593 neutrophil chemotaxis
GO:0030595 leukocyte chemotaxis
GO:0032148 activation of protein kinase B activity
GO:0032873 negative regulation of stress-activated MAPK cascade
GO:0032991 protein-containing complex
GO:0034389 lipid droplet organization
GO:0034599 cellular response to oxidative stress
GO:0035307 positive regulation of protein dephosphorylation
GO:0042118 endothelial cell activation
GO:0043209 myelin sheath
GO:0043231 intracellular membrane-bounded organelle
GO:0045069 regulation of viral genome replication
GO:0045070 positive regulation of viral genome replication
GO:0050714 positive regulation of protein secretion
GO:0051092 positive regulation of NF-kappaB transcription factor activity
GO:0060352 cell adhesion molecule production
GO:0061944 negative regulation of protein K48-linked ubiquitination
GO:0070527 platelet aggregation
GO:1902176 negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
GO:1903901 negative regulation of viral life cycle
GO:1904399 heparan sulfate binding
GO:2001233 regulation of apoptotic signaling pathway

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus
Secreted

Domains

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DomainNameCategoryType
IPR002130 Cyclophilin-type peptidyl-prolyl cis-trans isomerase domainDomainDomain
IPR020892 Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved siteSiteConserved site
IPR024936 Cyclophilin-type peptidyl-prolyl cis-trans isomeraseFamilyFamily
IPR029000 Cyclophilin-like domain superfamilyFamilyHomologous superfamily

Diseases

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