Entity Details

Primary name HS71B_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP17879
EntryNameHS71B_MOUSE
FullNameHeat shock 70 kDa protein 1B
TaxID10090
Evidenceevidence at protein level
Length642
SequenceStatuscomplete
DateCreated1990-08-01
DateModified2021-06-02

Ontological Relatives

GenesHspa1b

GO terms

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GOName
GO:0002199 zona pellucida receptor complex
GO:0005524 ATP binding
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
GO:0005813 centrosome
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0006457 protein folding
GO:0007339 binding of sperm to zona pellucida
GO:0009408 response to heat
GO:0016192 vesicle-mediated transport
GO:0016887 ATP hydrolysis activity
GO:0031072 heat shock protein binding
GO:0031625 ubiquitin protein ligase binding
GO:0032436 positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0034620 cellular response to unfolded protein
GO:0042026 protein refolding
GO:0043066 negative regulation of apoptotic process
GO:0043154 negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0044183 protein folding chaperone
GO:0044297 cell body
GO:0051082 unfolded protein binding
GO:0051085 chaperone cofactor-dependent protein refolding
GO:0051787 misfolded protein binding
GO:0090063 positive regulation of microtubule nucleation
GO:1901673 regulation of mitotic spindle assembly

Subcellular Location

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Subcellular Location
Cytoplasm

Domains

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DomainNameCategoryType
IPR013126 Heat shock protein 70 familyFamilyFamily
IPR018181 Heat shock protein 70, conserved siteSiteConserved site
IPR029047 Heat shock protein 70kD, peptide-binding domain superfamilyFamilyHomologous superfamily
IPR029048 Heat shock protein 70kD, C-terminal domain superfamilyFamilyHomologous superfamily
IPR043129 ATPase, nucleotide binding domainFamilyHomologous superfamily

Diseases

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Interactions

31 interactions

InteractorPartnerSourcesPublicationsLink
HS71B_MOUSEACTB_HUMANBioGRID10748209 details
HS71B_MOUSEHS90B_MOUSEBioGRID8157642 details
HS71B_MOUSEGRAB_HUMANBioGRID16798735 details
HS71B_MOUSETRAF6_MOUSEBioGRID, MINT16697380 details
HS71B_MOUSENEMO_MOUSEBioGRID, MINT16697380 19136968 details
HS71B_MOUSELYOX_MOUSEmatrixdb21536655 details
HS71B_MOUSEBAG3_MOUSEBioGRID11527400 details
HS71B_MOUSEBAG4_MOUSEBioGRID11527400 details
HS71B_MOUSEERG_MOUSEBioGRID21183741 details
HS71B_MOUSEPROF1_MOUSEBioGRID9463375 details
HS71B_MOUSEPROF2_MOUSEBioGRID9463375 details
HS71B_MOUSEDAAF4_HUMANBioGRID15189447 details
HS71B_MOUSESOCS1_MOUSEBioGRID15456882 details
HS71B_MOUSEK2C8_MOUSEBioGRID12231209 details
HS71B_MOUSENHLC1_MOUSEBioGRID19036738 details
HS71B_MOUSEEPM2A_MOUSEBioGRID19036738 details
HS71B_MOUSEATX3_MOUSEBioGRID15639784 details
HS71B_MOUSEP53_MOUSEBioGRID23251530 details
HS71B_MOUSEKCNB1_MOUSEBioGRID16008572 details
HS71B_MOUSEDNJB6_MOUSEBioGRID16260608 details
HS71B_MOUSERARA_MOUSEBioGRID18495661 details
HS71B_MOUSEBAG1_MOUSEBioGRID20516211 details
HS71B_MOUSEAF9_MOUSEBioGRID20159978 details
HS71B_MOUSECHIP_MOUSEBioGRID24251647 details
HS71B_MOUSEIL4RA_MOUSEBioGRID24251647 details
HS71B_MOUSEDNJB2_HUMANBioGRID22396390 details
HS71B_MOUSEMT3_MOUSEBioGRID15802640 17018872 details
HS71B_MOUSEHIF1A_MOUSEBioGRID28116619 details
HS71B_MOUSEUBQL2_MOUSEBioGRID27477512 details
HS71B_MOUSEH31_HUMANBioGRID25330109 details
HS71B_MOUSEBAG5_MOUSEBioGRID24510904 details