Entity Details

Primary name CATD_MOUSE
Entity type UniProt
Source Source Link

Details

AccessionP18242
EntryNameCATD_MOUSE
FullNameCathepsin D
TaxID10090
Evidenceevidence at protein level
Length410
SequenceStatuscomplete
DateCreated1990-11-01
DateModified2021-06-02

Ontological Relatives

GenesCtsd

GO terms

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GOName
GO:0000045 autophagosome assembly
GO:0004175 endopeptidase activity
GO:0004190 aspartic-type endopeptidase activity
GO:0005615 extracellular space
GO:0005739 mitochondrion
GO:0005764 lysosome
GO:0005765 lysosomal membrane
GO:0006508 proteolysis
GO:0008233 peptidase activity
GO:0010008 endosome membrane
GO:0016787 hydrolase activity
GO:0042159 lipoprotein catabolic process
GO:0042277 peptide binding
GO:0042470 melanosome
GO:0043065 positive regulation of apoptotic process
GO:0043280 positive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0045121 membrane raft
GO:0062023 collagen-containing extracellular matrix
GO:0070001 aspartic-type peptidase activity
GO:0070201 regulation of establishment of protein localization

Subcellular Location

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Subcellular Location
Lysosome
Melanosome
Secreted

Domains

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DomainNameCategoryType
IPR001461 Aspartic peptidase A1 familyFamilyFamily
IPR001969 Aspartic peptidase, active siteSiteActive site
IPR012848 Aspartic peptidase, N-terminalDomainDomain
IPR021109 Aspartic peptidase domain superfamilyFamilyHomologous superfamily
IPR033121 Peptidase family A1 domainDomainDomain
IPR033144 Cathepsin DFamilyFamily

Diseases

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Interactions

1 interaction

InteractorPartnerSourcesPublicationsLink
CATD_MOUSEMPRI_MOUSEBioGRID, IntAct20541250 details