Entity Details

Primary name CRY2_HUMAN
Entity type UniProt
Source Source Link

Details

AccessionQ49AN0
EntryNameCRY2_HUMAN
FullNameCryptochrome-2
TaxID9606
Evidenceevidence at protein level
Length593
SequenceStatuscomplete
DateCreated2006-11-28
DateModified2021-06-02

Ontological Relatives

GenesCRY2

GO terms

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GOName
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0000976 transcription cis-regulatory region binding
GO:0003677 DNA binding
GO:0003684 damaged DNA binding
GO:0003697 single-stranded DNA binding
GO:0005576 extracellular region
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0007623 circadian rhythm
GO:0009416 response to light stimulus
GO:0009785 blue light signaling pathway
GO:0009882 blue light photoreceptor activity
GO:0014823 response to activity
GO:0016607 nuclear speck
GO:0018298 protein-chromophore linkage
GO:0019902 phosphatase binding
GO:0032515 negative regulation of phosphoprotein phosphatase activity
GO:0032922 circadian regulation of gene expression
GO:0042593 glucose homeostasis
GO:0042752 regulation of circadian rhythm
GO:0042754 negative regulation of circadian rhythm
GO:0043153 entrainment of circadian clock by photoperiod
GO:0045892 negative regulation of transcription, DNA-templated
GO:0071949 FAD binding
GO:2000118 regulation of sodium-dependent phosphate transport
GO:2000323 negative regulation of glucocorticoid receptor signaling pathway

Subcellular Location

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Subcellular Location
Cytoplasm
Nucleus

Domains

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DomainNameCategoryType
IPR005101 Cryptochrome/DNA photolyase, FAD-binding domainDomainDomain
IPR006050 DNA photolyase, N-terminalDomainDomain
IPR014729 Rossmann-like alpha/beta/alpha sandwich foldFamilyHomologous superfamily
IPR036134 Cryptochrome/DNA photolyase, FAD-binding domain-like superfamilyFamilyHomologous superfamily
IPR036155 Cryptochrome/photolyase, N-terminal domain superfamilyFamilyHomologous superfamily

Diseases

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Interactions

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